{"id":"W4411871304","doi":"10.1016/j.ygyno.2025.06.003","title":"Patient-reported outcomes from the phase 3, randomized, double-blind, placebo-controlled ENGOT-cx11/GOG-3047/KEYNOTE-A18 study of pembrolizumab plus concurrent chemoradiotherapy in participants with high-risk locally advanced cervical cancer","year":2025,"lang":"en","type":"article","venue":"Gynecologic Oncology","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Merck Sharp and Dohme","keywords":"Medicine; Pembrolizumab; Placebo; Double blind; Internal medicine; Alternative medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003134444,0.00170124,0.00290395,0.0004267585,0.0006194875,0.0008153131,0.0007986588,0.001904052,0.007361462],"category_scores_gemma":[0.002900825,0.000570101,0.003302492,0.0004096376,0.0009546235,0.001188415,0.0004249986,0.003890681,0.0007880451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006677496,"about_ca_system_score_gemma":0.00100011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001113004,"about_ca_topic_score_gemma":0.002762264,"domain_scores_codex":[0.9989568,0.0005726034,0.00008818234,0.0001600128,0.00008994216,0.0001325307],"domain_scores_gemma":[0.9985136,0.0005802287,0.0004104053,0.00009876016,0.0001238226,0.000273159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.971131,0.005006513,0.001014501,0.001457603,0.003971078,0.00003060266,0.00005222401,0.0003176978,0.002316553,0.00007819905,0.001023854,0.0136003],"study_design_scores_gemma":[0.9353329,0.05441981,0.005502656,0.00007234856,0.003130353,0.00003750049,0.00003497877,0.0002286504,0.000441316,0.0001318426,0.0006448101,0.00002276763],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714165,0.01359228,0.001285714,0.0009327109,0.0006322745,0.004292438,0.004374299,0.0001426903,0.003330987],"genre_scores_gemma":[0.9861377,0.003943555,0.001418156,0.001174038,0.0003740552,0.002967668,0.002172437,0.00002687386,0.001785541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007361462,"threshold_uncertainty_score":0.02462655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04195995035766201,"score_gpt":0.3756118610146861,"score_spread":0.3336519106570241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}