{"id":"W4411871402","doi":"10.1016/j.bbrc.2025.152279","title":"Hydrogen sulfide mitigates iron-induced mitochondrial dysfunction in vascular smooth muscle cells","year":2025,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mitochondrion; Oxidative stress; Cell biology; Cystathionine gamma-lyase; Oxidative phosphorylation; Reactive oxygen species; Biology; Chemistry; Biochemistry; Internal medicine; Cystathionine beta synthase; Medicine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003992045,0.0004060239,0.0005733239,0.0001907651,0.0003244689,0.0003558327,0.0003542136,0.0006138073,0.001877388],"category_scores_gemma":[0.0002862506,0.0002056259,0.0004576395,0.0001675001,0.0003819515,0.0003737128,0.0004183261,0.0009864146,0.0002445905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002542521,"about_ca_system_score_gemma":0.0006531999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001785753,"about_ca_topic_score_gemma":0.002864359,"domain_scores_codex":[0.9998373,0.00004424556,0.00001728644,0.00001801638,0.00002593755,0.00005711664],"domain_scores_gemma":[0.9997659,0.00002966953,0.00004374402,0.00003818329,0.00004063339,0.00008187615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01080269,0.0007880245,0.0007334779,0.000230511,0.0001092128,0.000432758,0.0001613748,0.0003968333,0.9757633,0.0003490479,0.001000958,0.009231796],"study_design_scores_gemma":[0.0009830233,0.01404114,0.01934443,0.00005409938,0.0002508989,0.0002961927,0.0007293084,0.003089338,0.9554179,0.0004602999,0.005299806,0.00003357537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961135,0.000917401,0.001021111,0.0004611504,0.0002107934,0.00002736688,0.0001683316,0.0001136239,0.0009665417],"genre_scores_gemma":[0.9970725,0.0005222621,0.0004185431,0.0001149468,0.00004062123,0.00002008283,0.0002296657,0.000008305239,0.001573003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001877388,"threshold_uncertainty_score":0.006280541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03426072654901965,"score_gpt":0.3287998785116619,"score_spread":0.2945391519626423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}