{"id":"W4411875639","doi":"10.1152/physiol.2025.40.s1.1071","title":"Oxidized DNA repair enzymes protect skeletal muscle from oxidative stress during differentiation and contractile activity","year":2025,"lang":"en","type":"article","venue":"Physiology","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Oxidative stress; Skeletal muscle; Enzyme; Oxidative phosphorylation; Cell biology; DNA; Biochemistry; DNA repair; Chemistry; Oxidative enzyme; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002461038,0.0003177726,0.000325065,0.000318102,0.0002082658,0.0003000612,0.000201589,0.000357453,0.001035453],"category_scores_gemma":[0.0002026671,0.0001701623,0.0003280919,0.0002466384,0.0002421317,0.0002716255,0.0002235334,0.0004997181,0.0003021029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002337794,"about_ca_system_score_gemma":0.0002445385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001086948,"about_ca_topic_score_gemma":0.002246978,"domain_scores_codex":[0.9997528,0.00002812052,0.00002517997,0.00007185033,0.00006591572,0.0000561164],"domain_scores_gemma":[0.9998154,0.00001668658,0.00006946506,0.0000135506,0.00005461169,0.00003029918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001087075,0.00001555223,0.0009420021,0.0001192388,0.00001014735,0.00003980854,0.00005044691,0.00002012775,0.996903,0.00003650376,0.00002592034,0.001728546],"study_design_scores_gemma":[0.00001686209,0.0006405895,0.1209375,0.00008844797,0.00006445948,0.0003602381,0.0003175557,0.0004154344,0.8720987,0.0001329061,0.00491344,0.00001393811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788253,0.01438025,0.004267371,0.0002293286,0.00006681637,0.00004103385,0.0005762712,0.00006027479,0.00155348],"genre_scores_gemma":[0.9842433,0.005211271,0.004056733,0.0001566208,0.00002809625,0.00007140636,0.0009470317,0.00001664916,0.005268937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001086948,"threshold_uncertainty_score":0.003463924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004555297183626889,"score_gpt":0.2325746410494565,"score_spread":0.2280193438658297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}