{"id":"W4411875639","doi":"10.1152/physiol.2025.40.s1.1071","title":"Oxidized DNA repair enzymes protect skeletal muscle from oxidative stress during differentiation and contractile activity","year":2025,"lang":"en","type":"article","venue":"Physiology","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Oxidative stress; Skeletal muscle; Enzyme; Oxidative phosphorylation; Cell biology; DNA; Biochemistry; DNA repair; Chemistry; Oxidative enzyme; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004047053,0.0001551243,0.0002280542,0.00002668631,0.0001544846,0.00001062329,0.00006801227,0.0001167164,0.00001528751],"category_scores_gemma":[0.0001084672,0.0001399944,0.00008544174,0.00004766504,0.00008215239,0.000006064161,0.000207377,0.00009870485,0.00000208806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001410797,"about_ca_system_score_gemma":0.00001963877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000221673,"about_ca_topic_score_gemma":0.000187786,"domain_scores_codex":[0.9990914,0.0001363531,0.0001078531,0.00041469,0.0000438293,0.0002058533],"domain_scores_gemma":[0.9995672,0.0000637202,0.00007541681,0.0002231328,0.00003901067,0.00003158895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002338612,0.00008625639,0.0005327791,0.00004219001,0.0001958729,9.38428e-7,0.00004152403,0.000003887461,0.9975618,0.00003237676,0.0007028944,0.0005655813],"study_design_scores_gemma":[0.0006544793,0.00008477607,0.3946816,0.00001393578,0.00002388743,2.886459e-7,0.00003913542,0.00007476714,0.6036257,0.00008139577,0.00062485,0.00009515567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984263,0.000722278,0.000119915,0.0001112641,0.0001520571,0.0003109373,0.00004970668,0.00003429447,0.00007324347],"genre_scores_gemma":[0.9992336,0.000168721,0.0000461928,0.00005354688,0.0001707291,0.0001004367,0.00008074289,0.000009210175,0.0001368293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3941488,"threshold_uncertainty_score":0.5708805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004555297183626889,"score_gpt":0.2325746410494565,"score_spread":0.2280193438658297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}