{"id":"W4411876154","doi":"10.1152/physiol.2025.40.s1.0427","title":"Skeletal Muscle Health and Mitochondrial Function are Regulated By The Transcription Factor ATF5 During Aging","year":2025,"lang":"en","type":"article","venue":"Physiology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Skeletal muscle; Activating transcription factor; Transcription factor; Mitochondrion; Biology; Cell biology; Genetics; Anatomy; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001516334,0.0002604833,0.0002086552,0.0002362153,0.0001379701,0.0001855784,0.0001560941,0.0002612309,0.000822024],"category_scores_gemma":[0.0001109933,0.0001082034,0.0002899158,0.0001224417,0.0002135249,0.0002756628,0.0002189678,0.0002395948,0.0001426291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000222712,"about_ca_system_score_gemma":0.00009477245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008116721,"about_ca_topic_score_gemma":0.001092249,"domain_scores_codex":[0.9999008,0.000008817895,0.00001306445,0.00003052149,0.0000240026,0.00002275605],"domain_scores_gemma":[0.9998934,0.000004532213,0.00005414418,0.000006443159,0.00001652579,0.00002493471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000262287,0.00001722849,0.002358465,0.00004325901,0.000007363305,0.00007930135,0.00004485836,0.00002927531,0.9950708,0.00004903646,0.00004176054,0.001996448],"study_design_scores_gemma":[0.00002222562,0.001169683,0.4625899,0.00005672195,0.00008789575,0.001003175,0.0003172284,0.0009396609,0.5301574,0.0002779583,0.003359028,0.00001912235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949273,0.002401477,0.001433449,0.00008091469,0.00002217976,0.000009786183,0.0004111718,0.00003553952,0.0006782332],"genre_scores_gemma":[0.9954282,0.001070879,0.001279108,0.00007781867,0.00001006308,0.00002571207,0.000438173,0.000009569912,0.00166034],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000822024,"threshold_uncertainty_score":0.002749979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01284024021781634,"score_gpt":0.2674385375987797,"score_spread":0.2545982973809633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}