{"id":"W4411887265","doi":"10.1016/j.esmogo.2025.100190","title":"Systemic adjuvant and perioperative chemotherapy following curative-intent liver metastasectomy in colorectal cancer—is it justified?","year":2025,"lang":"en","type":"article","venue":"ESMO Gastrointestinal Oncology","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia; BC Cancer Agency","funders":"","keywords":"Metastasectomy; Medicine; Colorectal cancer; Perioperative; Adjuvant chemotherapy; Chemotherapy; General surgery; Adjuvant; Oncology; Cancer; Internal medicine; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002228368,0.0001237927,0.0005804399,0.0002500918,0.0001937872,0.001041913,0.000253596,0.0005137542,0.00178451],"category_scores_gemma":[0.01064652,0.00007711419,0.0004060448,0.000382207,0.0005473264,0.001094327,0.0003092651,0.0008097293,0.000339748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005265197,"about_ca_system_score_gemma":0.001253742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006320797,"about_ca_topic_score_gemma":0.002391307,"domain_scores_codex":[0.9988425,0.0006487308,0.0001528667,0.00008779583,0.0001715777,0.00009653186],"domain_scores_gemma":[0.995903,0.001703505,0.001408901,0.0001961821,0.0004143655,0.0003741774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007057588,0.0002444772,0.1064289,0.002543008,0.0006220499,0.0004665993,0.000301739,0.0009197954,0.001516292,0.00313578,0.0100742,0.8666895],"study_design_scores_gemma":[0.001933665,0.01843147,0.6006251,0.01798583,0.00631195,0.0105215,0.004022504,0.006379736,0.008276335,0.03277477,0.2924307,0.0003064787],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.4050743,0.5250648,0.003112677,0.04919292,0.002298094,0.0001033343,0.0005126652,0.00006805738,0.01457303],"genre_scores_gemma":[0.9227096,0.06877654,0.001146997,0.004483207,0.001715421,0.00005575861,0.0002573955,0.00002087583,0.0008341954],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.002228368,"threshold_uncertainty_score":0.01178485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05475863086939123,"score_gpt":0.3313500623016415,"score_spread":0.2765914314322503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}