{"id":"W4411895830","doi":"10.3390/cells14131002","title":"Growth Hormone Secretagogue Receptor (GHSR) Is Elevated in Myocardial Tissues of DMD mdx:utrn−/− Mice, and Correlates Strongly with Inflammatory Markers, and Negatively with Cardiac Function","year":2025,"lang":"en","type":"article","venue":"Cells","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Growth hormone secretagogue receptor; Ghrelin; Internal medicine; Endocrinology; Secretagogue; Receptor; Cardiac function curve; Hormone; Medicine; Biology; Heart failure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002790704,0.0007011757,0.0004019404,0.001200498,0.0003169336,0.0003056498,0.000236833,0.0006818469,0.003153348],"category_scores_gemma":[0.0001621842,0.0004162671,0.0003641324,0.0002722026,0.0006548835,0.0002973719,0.0003250253,0.000807607,0.0006016484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003118564,"about_ca_system_score_gemma":0.0001421968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005984035,"about_ca_topic_score_gemma":0.001078659,"domain_scores_codex":[0.9995545,0.00004243186,0.00006687103,0.0001576757,0.0001154825,0.00006306281],"domain_scores_gemma":[0.9996868,0.00002757993,0.0001184102,0.00002078111,0.00002240414,0.0001239883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002139276,0.00002363655,0.0008084871,0.00003297676,0.000007264004,0.00009775881,0.00002039196,0.00001566207,0.9983261,0.00003587611,0.00003550372,0.0003823084],"study_design_scores_gemma":[0.0001369256,0.001327545,0.2064199,0.0000547231,0.0001163132,0.003883052,0.000354555,0.001420822,0.7820975,0.0002140331,0.003942157,0.00003235272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930196,0.001346951,0.002745963,0.000211664,0.00004661589,0.0000223425,0.001718736,0.0001027582,0.0007853389],"genre_scores_gemma":[0.9841546,0.001313913,0.005296101,0.0002681014,0.00004003191,0.0001528527,0.002352837,0.0000996711,0.006321883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003153348,"threshold_uncertainty_score":0.01054901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004952875657753531,"score_gpt":0.1927656208821985,"score_spread":0.187812745224445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}