{"id":"W4411895830","doi":"10.3390/cells14131002","title":"Growth Hormone Secretagogue Receptor (GHSR) Is Elevated in Myocardial Tissues of DMD mdx:utrn−/− Mice, and Correlates Strongly with Inflammatory Markers, and Negatively with Cardiac Function","year":2025,"lang":"en","type":"article","venue":"Cells","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Growth hormone secretagogue receptor; Ghrelin; Internal medicine; Endocrinology; Secretagogue; Receptor; Cardiac function curve; Hormone; Medicine; Biology; Heart failure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605065,0.0001764115,0.0002955789,0.0001608078,0.00008144919,0.00004271599,0.00007280437,0.00009741048,0.00001679986],"category_scores_gemma":[0.00002955287,0.0001444225,0.00002657843,0.0003849481,0.0003027045,0.0002558081,0.00004887415,0.0001507882,0.000005671928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002542586,"about_ca_system_score_gemma":0.0000651407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000563678,"about_ca_topic_score_gemma":0.00001162013,"domain_scores_codex":[0.9988938,0.0001246047,0.000219259,0.0003813641,0.000197749,0.0001832031],"domain_scores_gemma":[0.9994124,0.0001721847,0.0001335605,0.0001425058,0.00007663424,0.00006275459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001727176,0.00004809281,0.167336,0.0001277972,0.00006607594,0.000005876345,0.0007699867,0.00005339079,0.8266261,0.0006594233,0.001832063,0.0007480757],"study_design_scores_gemma":[0.001330496,0.0004513572,0.4161291,0.0001404916,0.00005708307,0.000001430406,0.0003157573,0.0001918975,0.5784039,0.0001052303,0.002674102,0.000199238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997604,0.0003730719,0.0000851158,0.0001154253,0.000103657,0.0003772057,0.00003103612,0.0000311322,0.001279433],"genre_scores_gemma":[0.9981411,0.0006136139,0.0001721769,0.00006233736,0.00002457126,0.000009427805,0.000008122807,0.00001407827,0.000954618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.248793,"threshold_uncertainty_score":0.5889378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004952875657753531,"score_gpt":0.1927656208821985,"score_spread":0.187812745224445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}