{"id":"W4411902124","doi":"10.1186/s40644-025-00899-5","title":"Imaging-derived biomarkers from 68Ga-DOTATOC PET/CT scans to predict survival of patients with neuroendocrine tumors after PRRT with 177Lu-DOTATATE","year":2025,"lang":"en","type":"article","venue":"Cancer Imaging","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"Technische Universität Dresden","keywords":"Medicine; Radionuclide therapy; Neuroendocrine tumors; Radiomics; Proportional hazards model; Octreotide; Radiology; Nuclear medicine; Standardized uptake value; Internal medicine; Oncology; Positron emission tomography; Somatostatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007567591,0.0005140402,0.0007339814,0.0005216984,0.0001060092,0.0000647186,0.0003760268,6.361163e-7,0.000174995],"category_scores_gemma":[0.0001697505,0.0004027631,0.00009526255,0.001110087,0.0005902115,0.0005151955,0.0002697585,0.0003838505,0.000009326385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002489836,"about_ca_system_score_gemma":0.0006449696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001581028,"about_ca_topic_score_gemma":0.0003862916,"domain_scores_codex":[0.9963734,0.0001193501,0.0005353699,0.001015277,0.0009519372,0.001004638],"domain_scores_gemma":[0.9978261,0.0001540028,0.0001952823,0.0008119718,0.0005485806,0.0004640512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006664,0.0001943187,0.9581994,0.0002765559,0.0002553161,0.02903971,0.00004149159,0.00008180067,0.001771956,0.000003730048,0.001173178,0.002298503],"study_design_scores_gemma":[0.01081306,0.0005352692,0.9503942,0.002410929,0.000393144,0.001120426,0.0006129476,0.0006922613,0.02559751,0.00003650118,0.006777394,0.0006163315],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919699,0.0005895178,0.0002634397,0.003571907,0.0003360086,0.001672043,0.0005739005,0.0001719142,0.0008513617],"genre_scores_gemma":[0.9963784,0.00005483537,0.001024237,0.001452494,0.00005407244,0.0004663074,0.00009666369,0.000121641,0.0003514108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02791929,"threshold_uncertainty_score":0.9998424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006860658559540462,"score_gpt":0.2805414539745413,"score_spread":0.2736807954150008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}