{"id":"W4411923937","doi":"10.1016/j.bneo.2025.100132","title":"Posttranscriptional activity of eIF4E contributes to HoxA9-driven leukemogenesis","year":2025,"lang":"en","type":"article","venue":"Blood Neoplasia","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; Canada Research Chairs","keywords":"EIF4E; Biology; Genetics; Translation (biology); Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001442527,0.0001928189,0.000375077,0.0002362176,0.00021611,0.00001169892,0.0003294245,0.0002274403,0.0001683408],"category_scores_gemma":[0.00008991187,0.0001901808,0.0001720712,0.0004348502,0.000187774,0.00007078264,0.00008141679,0.0001845392,0.0001527978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002565778,"about_ca_system_score_gemma":0.0002076092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001917647,"about_ca_topic_score_gemma":0.00001801276,"domain_scores_codex":[0.9988777,0.0001198335,0.0003030156,0.0002994532,0.00004139094,0.0003586269],"domain_scores_gemma":[0.9993394,0.000149299,0.00008026621,0.0003136238,0.0001104248,0.00000700943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003379635,0.0005143691,0.003710295,0.00003644943,0.0004669982,0.000001365249,0.0001930854,0.00005547117,0.9819227,0.005963455,0.0006916923,0.006106137],"study_design_scores_gemma":[0.002809678,0.0001622803,0.1451034,0.00009642527,0.0002362398,0.000009739549,0.000171549,0.000005400998,0.8091612,0.0002600864,0.04178031,0.0002036229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9834005,0.01109951,0.000881219,0.00100153,0.0009701643,0.0003193305,0.000102504,0.00006869529,0.002156609],"genre_scores_gemma":[0.99674,0.00006103938,0.00004171538,0.0003637486,0.000002223905,0.00003438465,0.00005026788,0.00001023615,0.002696423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1727615,"threshold_uncertainty_score":0.7755349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005928059311746098,"score_gpt":0.2275228559210846,"score_spread":0.2215947966093385,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}