{"id":"W4411929791","doi":"10.3390/biom15070929","title":"Regeneration of Insulin-Producing β Cells, Reduction in Inflammation and Oxidation Stress, and Improvement in Lipid Profile in a Type 1 Diabetes Rat Model by Intraperitoneal Injection of the Growth Factors-Rich Catfish Skin-Derived Fraction-B: An Introductory Report","year":2025,"lang":"en","type":"article","venue":"Biomolecules","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; Kuwait University","keywords":"Insulin; Regeneration (biology); Catfish; Diabetes mellitus; Oxidative stress; Internal medicine; Inflammation; Intraperitoneal injection; Endocrinology; Streptozotocin; Pancreatic islets; Type 1 diabetes; Medicine; Islet; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001980861,0.0007184196,0.0002866403,0.00058234,0.0001772854,0.0002102645,0.0001590159,0.0003620077,0.00161729],"category_scores_gemma":[0.00006355636,0.0001233909,0.0004059703,0.0002008994,0.000227644,0.0002593234,0.0001538077,0.0006838757,0.0001942443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001557582,"about_ca_system_score_gemma":0.0002072581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004016112,"about_ca_topic_score_gemma":0.0007170727,"domain_scores_codex":[0.9999262,0.000007837084,0.000007011209,0.00001830677,0.00002021283,0.00002030307],"domain_scores_gemma":[0.9999176,0.000007275452,0.00002535716,0.000007896593,0.0000100673,0.00003175645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004335734,0.0002055314,0.0002851692,0.00009862989,0.000006757745,0.0000535813,0.00001926847,0.0000332633,0.995023,0.00005793034,0.0000325469,0.003750785],"study_design_scores_gemma":[0.00005843479,0.004063622,0.005047687,0.00002287384,0.00004376129,0.000238533,0.00004578689,0.0002142744,0.9880232,0.00004684409,0.002187257,0.0000076929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933629,0.002953557,0.001889484,0.0001312247,0.00004492089,0.00004527999,0.0001679414,0.00006378545,0.00134093],"genre_scores_gemma":[0.9821168,0.004717364,0.006349929,0.0001078641,0.00003754312,0.00009188321,0.0004752313,0.00002931059,0.006074126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00161729,"threshold_uncertainty_score":0.005410373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006959247435248062,"score_gpt":0.2291783782868824,"score_spread":0.2222191308516343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}