{"id":"W4411929791","doi":"10.3390/biom15070929","title":"Regeneration of Insulin-Producing β Cells, Reduction in Inflammation and Oxidation Stress, and Improvement in Lipid Profile in a Type 1 Diabetes Rat Model by Intraperitoneal Injection of the Growth Factors-Rich Catfish Skin-Derived Fraction-B: An Introductory Report","year":2025,"lang":"en","type":"article","venue":"Biomolecules","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; Kuwait University","keywords":"Insulin; Regeneration (biology); Catfish; Diabetes mellitus; Oxidative stress; Internal medicine; Inflammation; Intraperitoneal injection; Endocrinology; Streptozotocin; Pancreatic islets; Type 1 diabetes; Medicine; Islet; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002776711,0.0001178122,0.0002269554,0.0003253641,0.00003451007,0.00001439693,0.00002984914,0.0001020676,0.000002603501],"category_scores_gemma":[0.0003159691,0.0001010276,0.0000155056,0.0005289358,0.00008827518,0.0002253839,0.00002526134,0.000113059,5.849916e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001358303,"about_ca_system_score_gemma":0.0001353583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007910513,"about_ca_topic_score_gemma":0.0002237288,"domain_scores_codex":[0.9988666,0.00008999802,0.0004917918,0.0003036507,0.0001408908,0.0001070637],"domain_scores_gemma":[0.9993819,0.0000242577,0.0002260374,0.0001884439,0.0001545936,0.00002476695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001149939,0.0001440833,0.09799199,0.0002284165,0.00001175246,2.466278e-7,0.0006225493,0.0001581635,0.8986727,0.00003011376,0.00004523205,0.001979792],"study_design_scores_gemma":[0.0006187517,0.0001459725,0.1066997,0.0001603191,0.00002536723,0.000001118119,0.0005612781,0.00650582,0.8851314,0.00007954158,0.000002786055,0.00006793084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984317,0.0003473686,0.0001106552,0.0002716694,0.0002536078,0.0005481151,0.000005385137,0.0000123954,0.00001904058],"genre_scores_gemma":[0.9991154,0.0001791501,0.0003878194,0.00001428028,0.00005420077,0.00003495347,0.0001814551,0.000008415604,0.00002429224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0135413,"threshold_uncertainty_score":0.4119787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006959247435248062,"score_gpt":0.2291783782868824,"score_spread":0.2222191308516343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}