{"id":"W4411937924","doi":"10.1111/cea.70100","title":"Towards Personalised Therapy in Chronic Spontaneous Urticaria: Advancing From Endotype to Clinical Response","year":2025,"lang":"en","type":"review","venue":"Clinical & Experimental Allergy","topic":"Urticaria and Related Conditions","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Health Research Board; Health Service Executive; Wellcome Trust; Canadian Institute for Theoretical Astrophysics","keywords":"Omalizumab; Medicine; Endotype; Autoantibody; Immunoglobulin E; Immunology; Allergy; Immunopathology; Antibody; Asthma","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001906268,0.0005579591,0.0009814627,0.001708494,0.0002178522,0.001949646,0.0007048458,0.001123726,0.001827592],"category_scores_gemma":[0.002503305,0.0002670211,0.0006222092,0.001043729,0.0006121761,0.001835289,0.0008729392,0.00205422,0.0009356554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009914346,"about_ca_system_score_gemma":0.0008380545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000625434,"about_ca_topic_score_gemma":0.001182443,"domain_scores_codex":[0.999027,0.0004063247,0.000232709,0.0001110108,0.0001778921,0.00004506429],"domain_scores_gemma":[0.9989972,0.0005669867,0.0001665518,0.00003043794,0.0002016938,0.00003705176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001888232,0.0001113944,0.0008487441,0.03848424,0.0001936898,0.0005239121,0.0008053792,0.0008074384,0.002369081,0.008252906,0.02585682,0.9215576],"study_design_scores_gemma":[0.00006842351,0.0005407974,0.004134168,0.02811336,0.000402998,0.004247364,0.000554379,0.0006087393,0.000869452,0.006060811,0.9543296,0.00006983941],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009931646,0.9916576,0.001579566,0.003071749,0.0005799783,0.00005156257,0.00004266473,0.00002927878,0.001994447],"genre_scores_gemma":[0.005866973,0.9879891,0.001969224,0.002258491,0.0009013216,0.00007072834,0.00007066692,0.00000796621,0.0008655097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001949646,"threshold_uncertainty_score":0.01008141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07712463404175617,"score_gpt":0.4594525285461449,"score_spread":0.3823278945043888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}