{"id":"W4411963060","doi":"10.3390/antibiotics14070671","title":"Synthetic Human Lactoferrin Peptide hLF(1-11) Shows Antifungal Activity and Synergism with Fluconazole and Anidulafungin Towards Candida albicans and Various Non-Albicans Candida Species, Including Candidozyma auris","year":2025,"lang":"en","type":"article","venue":"Antibiotics","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"TC Scientific (Canada)","funders":"","keywords":"Candida auris; Fluconazole; Anidulafungin; Candida albicans; Microbiology; Broth microdilution; Corpus albicans; Lactoferrin; Minimum inhibitory concentration; Biology; Caspofungin; Peptide; Antifungal; Antibiotics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001469631,0.0002826217,0.0002167767,0.0001504857,0.00009139467,0.0001622706,0.000122358,0.0001786615,0.0007820078],"category_scores_gemma":[0.000124719,0.00005754103,0.000170358,0.0001242693,0.0001580029,0.0001182451,0.0001480701,0.0001971833,0.0001343512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001100895,"about_ca_system_score_gemma":0.000121905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002556622,"about_ca_topic_score_gemma":0.0003171291,"domain_scores_codex":[0.9998851,0.00002203652,0.00001095179,0.00002179383,0.00004106197,0.00001911826],"domain_scores_gemma":[0.9999015,0.00001945429,0.00003590953,0.000006455247,0.00001077431,0.00002599434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004904566,0.000143395,0.001804718,0.000125131,0.0000123713,0.00008861412,0.00001204197,0.0000906812,0.989343,0.00001175265,0.00004440098,0.007833301],"study_design_scores_gemma":[0.0001290737,0.00983312,0.05924197,0.00003003136,0.00007845368,0.003291513,0.00007486602,0.0005322805,0.9231735,0.00003184559,0.003568626,0.00001471385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952493,0.003876077,0.0002685894,0.00003730337,0.0000126737,0.00001678746,0.0001108799,0.000008067659,0.0004203026],"genre_scores_gemma":[0.9975364,0.001243869,0.000545124,0.00002850408,0.0000125509,0.000009040873,0.000271339,0.000001813718,0.0003512178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007820078,"threshold_uncertainty_score":0.002616107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0100344483654356,"score_gpt":0.2347535565257975,"score_spread":0.2247191081603619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}