{"id":"W4411978280","doi":"10.1139/cjm-2024-0073","title":"VeA is involved in anti-tumor activity by regulating adenylosuccinate lyase to mediate the synthesis of Acadesine in endophytic <i>Fusarium solani</i>","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Transcriptome; Downregulation and upregulation; Biology; Biosynthesis; Enzyme; Gene; Molecular biology; Biochemistry; Gene expression","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001199602,0.0004145632,0.0003323517,0.0002905797,0.000257092,0.0005430451,0.0002000274,0.0003729421,0.001431574],"category_scores_gemma":[0.000136519,0.000150113,0.000418953,0.0001772589,0.0002417935,0.0002701943,0.0002652404,0.0004701205,0.0005639513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000424935,"about_ca_system_score_gemma":0.0002161674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007826106,"about_ca_topic_score_gemma":0.0008353203,"domain_scores_codex":[0.9998436,0.00001971429,0.00001319629,0.00005245826,0.0000426079,0.00002844308],"domain_scores_gemma":[0.9998482,0.00002378642,0.00005909769,0.00001459372,0.00002352715,0.00003076154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007991894,0.000009974659,0.0003606478,0.00003990701,0.000005863532,0.00007662354,0.000009074006,0.00005317843,0.9976513,0.0001110517,0.00005176476,0.001550741],"study_design_scores_gemma":[0.00002216017,0.0002444927,0.02107739,0.0000191347,0.00004393586,0.0008018471,0.00008351287,0.00233578,0.9623282,0.0001790376,0.0128493,0.00001515901],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738704,0.009672048,0.008976335,0.000374654,0.000112441,0.00005502519,0.001928803,0.0005305366,0.004479777],"genre_scores_gemma":[0.9909394,0.001201024,0.002704692,0.0001218548,0.00001287502,0.00002509231,0.001437763,0.00005366956,0.003503682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001431574,"threshold_uncertainty_score":0.004789114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009669281793801625,"score_gpt":0.2302732677847459,"score_spread":0.2206039859909443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}