{"id":"W4411984854","doi":"10.1093/molbev/msaf161","title":"Host-Specific Adaptation of <i>Legionella pneumophila</i> to Single and Multiple Hosts","year":2025,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec; Vetenskapsrådet; Fonds de recherche du Québec – Nature et technologies; Carl Tryggers Stiftelse för Vetenskaplig Forskning","keywords":"Biology; Legionella pneumophila; Effector; Gene; Microbiology; Legionnaires' disease; Population; Virulence; Host (biology); Legionella; Genetics; Bacteria; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002004608,0.0002487051,0.0003194349,0.0002941472,0.0001685253,0.0003881229,0.0002540483,0.0003744405,0.0006728689],"category_scores_gemma":[0.0004255484,0.0001383154,0.0002296017,0.0001836413,0.0001985048,0.0002203802,0.0003934569,0.0003265435,0.0001315451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003078828,"about_ca_system_score_gemma":0.0001786884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005325602,"about_ca_topic_score_gemma":0.000785258,"domain_scores_codex":[0.9996694,0.00005158134,0.00002613136,0.0001165115,0.00006866519,0.00006777641],"domain_scores_gemma":[0.9996853,0.00005972011,0.00009756533,0.00006050411,0.00004834281,0.00004851545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00007273418,0.00002177053,0.005508085,0.00001877826,0.000007577435,0.00006959061,0.00002607643,0.0001029469,0.9927602,0.00002922533,0.00001755135,0.001365464],"study_design_scores_gemma":[0.00002288122,0.001035907,0.2540863,0.00002696643,0.00007610514,0.002119883,0.0003418876,0.00351863,0.7354562,0.00013538,0.003147664,0.00003229589],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999233,0.0001599205,0.0002697576,0.00001419689,0.000003653268,0.000006103759,0.00007571028,0.000009877652,0.0002277543],"genre_scores_gemma":[0.9986928,0.0001202186,0.0006121405,0.0000271866,0.000003631609,0.00001320198,0.0002064673,0.000008051808,0.000316215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006728689,"threshold_uncertainty_score":0.002250969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01089932472201047,"score_gpt":0.2625876283426891,"score_spread":0.2516883036206786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}