{"id":"W4411988364","doi":"10.1016/j.drugalcdep.2025.112778","title":"A multi-site study examining the tobacco withdrawal trajectory in people with tobacco and cannabis co-use","year":2025,"lang":"en","type":"article","venue":"Drug and Alcohol Dependence","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; Fonds de Recherche du Québec - Santé; National Institute on Drug Abuse; Tobacco-Related Disease Research Program","keywords":"Cannabis; Tobacco use; Psychology; Addiction; Medicine; Environmental health; Psychiatry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001088713,0.0003017704,0.000579517,0.0005151414,0.00116437,0.0005029541,0.0003628228,0.0006118981,0.001877803],"category_scores_gemma":[0.001484338,0.0004890675,0.0006370221,0.000680448,0.0003679147,0.0005889567,0.0006933503,0.0008012131,0.0005573637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004794711,"about_ca_system_score_gemma":0.000576081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009279483,"about_ca_topic_score_gemma":0.01691093,"domain_scores_codex":[0.9993088,0.0002837376,0.00004925442,0.0001500981,0.0001100063,0.00009821133],"domain_scores_gemma":[0.9988826,0.0001323658,0.0002958459,0.0001268948,0.0002023784,0.0003598644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005168692,0.002223443,0.9809138,0.0001059627,0.0002652653,0.0002011019,0.002118002,0.00004951058,0.002478575,0.00002514082,0.0002659553,0.006184548],"study_design_scores_gemma":[0.0003415638,0.004753674,0.9925885,0.00001520414,0.0001370697,0.0002610303,0.001208266,0.0001547388,0.0001374446,0.00002555143,0.0003622872,0.000014627],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993999,0.00005805131,0.00009578758,0.00001477419,0.000003240084,0.0001313297,0.0001596107,0.00000221151,0.0001351539],"genre_scores_gemma":[0.9987535,0.00005796471,0.0002860534,0.00004961981,0.00000960537,0.0002076475,0.0002464087,0.000002530385,0.0003866137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009279483,"threshold_uncertainty_score":0.01845098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02372387113621187,"score_gpt":0.3101261494322675,"score_spread":0.2864022782960556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}