{"id":"W4411995564","doi":"10.1136/bcr-2025-265205","title":"Multiday intravenous ketamine infusion therapy for the management of central sensitisation syndrome secondary to chronic chemotherapy–induced peripheral neuropathic pain","year":2025,"lang":"en","type":"article","venue":"BMJ Case Reports","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Ketamine; Chronic pain; Anesthesia; Refractory (planetary science); Analgesic; Neuropathic pain; Cancer pain; Cancer; Internal medicine; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009707345,0.0001681596,0.0003000328,0.00008482182,0.0001091513,0.00001182302,0.0000291053,0.00006670717,0.0001829431],"category_scores_gemma":[0.00002524615,0.0001239831,0.0001313813,0.0001871722,0.00003137816,0.00002747255,0.0000278722,0.0001112226,7.475428e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002680875,"about_ca_system_score_gemma":0.0002482751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001829799,"about_ca_topic_score_gemma":0.00006362883,"domain_scores_codex":[0.9987346,0.0001245866,0.0004398898,0.0002938726,0.0001523759,0.0002546598],"domain_scores_gemma":[0.999181,0.0001433955,0.0001687629,0.0003501734,0.00008448009,0.00007222884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001138056,0.0004966221,0.001218246,0.0006981597,0.0008415488,0.1362559,0.0009465034,0.0001648564,0.04633553,0.00001961398,0.001117389,0.8107676],"study_design_scores_gemma":[0.02326435,0.01049185,0.4041016,0.001548135,0.001842395,0.400892,0.001016113,0.01396497,0.07266284,0.0001245579,0.06921002,0.0008812511],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890046,0.0007100413,0.002166174,0.00298147,0.0007131287,0.004143785,0.000005884578,0.00004055485,0.0002343934],"genre_scores_gemma":[0.9961938,0.0003607637,0.0002765667,0.001627985,0.00014652,0.0003184306,0.00003709184,0.0000231125,0.001015754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8098863,"threshold_uncertainty_score":0.5055882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782999677625906,"score_gpt":0.3177020947320485,"score_spread":0.2998720979557894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}