{"id":"W4412030878","doi":"10.1016/j.bioadv.2025.214403","title":"Hydrazone-crosslinked poly(oligoethylene glycol methacrylate)-based hydrogels with physically entrapped phage effectively control Pseudomonas aeruginosa infections in a burn wound model","year":2025,"lang":"en","type":"article","venue":"Biomaterials Advances","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Self-healing hydrogels; Pseudomonas aeruginosa; Burn wound; Methacrylate; Microbiology; Antibiotics; Wound healing; Bacteriophage; Bacteria; Materials science; Chemistry; Polymer chemistry; Medicine; Biology; Immunology; Composite material; Polymer; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008586626,0.0002713364,0.0001089038,0.00009501586,0.00006621871,0.0001206071,0.00009477651,0.0001557141,0.0005718384],"category_scores_gemma":[0.00006398484,0.00009886062,0.0001131602,0.00006071048,0.0001081118,0.0001659894,0.0001017604,0.0002535854,0.00007347207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001008993,"about_ca_system_score_gemma":0.0001018141,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002707101,"about_ca_topic_score_gemma":0.0006650168,"domain_scores_codex":[0.9999491,0.000006705504,0.000003670954,0.00001133834,0.00001696576,0.00001219904],"domain_scores_gemma":[0.9999372,0.00001023179,0.00002634542,0.000003694466,0.000005653096,0.00001691481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002435833,0.00001055053,0.00001919706,0.00001337001,0.000001149947,0.000009014851,0.000003227238,0.00004198835,0.9995071,0.0000139277,0.000006110682,0.0003501419],"study_design_scores_gemma":[0.000003468233,0.0001545532,0.0003482525,0.000002101499,0.000003794335,0.00002665581,0.000003727075,0.0004370325,0.9987447,0.000005692702,0.0002683501,0.000001664264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946826,0.0007067316,0.003784466,0.00003468888,0.00002299663,0.0000227665,0.00007053153,0.00004913452,0.0006260489],"genre_scores_gemma":[0.9930172,0.0005060396,0.004734743,0.00002641058,0.000006782449,0.00002405607,0.00005302893,0.00001543869,0.001616338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005718384,"threshold_uncertainty_score":0.001913011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009252175986906119,"score_gpt":0.3009578496938774,"score_spread":0.2917056737069713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}