{"id":"W4412063527","doi":"10.1007/s12325-025-03295-4","title":"Comparative Effectiveness of FF/UMEC/VI and BUD/GLY/FORM in Patients with COPD Stepping Up From Dual Therapy","year":2025,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact; Group for Research in Decision Analysis; GlaxoSmithKline (Canada)","funders":"","keywords":"Medicine; COPD; Internal medicine; Dual (grammatical number); Rheumatology; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002396181,0.0002367215,0.0006635554,0.0002622668,0.00004681298,0.00001185213,0.000122768,0.00007002355,0.00005404608],"category_scores_gemma":[0.00001937631,0.0001814267,0.00004326863,0.0005569379,0.0003410687,0.0003419406,0.0000473799,0.0002765967,0.000001558361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002818593,"about_ca_system_score_gemma":0.0001889246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002286075,"about_ca_topic_score_gemma":0.0001128518,"domain_scores_codex":[0.9983361,0.0002460146,0.0003039677,0.0004413854,0.0003634102,0.0003091497],"domain_scores_gemma":[0.9987722,0.0005974327,0.00009978921,0.0003007539,0.000158508,0.00007133248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01572878,0.0006583331,0.8915459,0.0002245832,0.0001728546,0.00001600607,0.001082192,0.00008586016,0.001041394,0.0003431599,0.000004247107,0.08909671],"study_design_scores_gemma":[0.0196337,0.0006337931,0.9686013,0.0009328537,0.00000938732,6.454695e-7,0.0005861601,0.0001423864,0.006641848,0.001887988,0.0007658526,0.0001640834],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9733864,0.02347515,0.00008550193,0.00004331984,0.0001439575,0.001573622,0.00005113663,0.00001774714,0.001223156],"genre_scores_gemma":[0.9961783,0.003316783,0.0001557058,0.00007565632,0.00002296024,0.0001201,0.00006500263,0.00001919752,0.00004629572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08893263,"threshold_uncertainty_score":0.7398365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01297490481521512,"score_gpt":0.3277930182503548,"score_spread":0.3148181134351397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}