{"id":"W4412072951","doi":"10.1016/j.conb.2025.103086","title":"Cracking the cadherin codes that wire the nervous system","year":2025,"lang":"en","type":"review","venue":"Current Opinion in Neurobiology","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Neuroscience; Cadherin; Nervous system; Cracking; Biology; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006589568,0.0009708498,0.001133513,0.001498372,0.0002918853,0.001575928,0.001264511,0.001973275,0.002604452],"category_scores_gemma":[0.0007624425,0.0004089795,0.0002901509,0.0014716,0.001529603,0.002632317,0.001034928,0.002989997,0.002181729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001024834,"about_ca_system_score_gemma":0.001023611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001265227,"about_ca_topic_score_gemma":0.002950415,"domain_scores_codex":[0.999821,0.00002209803,0.00001968152,0.00003911279,0.00007383333,0.00002438427],"domain_scores_gemma":[0.9997725,0.00008493604,0.00004031382,0.00001053865,0.00006294777,0.0000288337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001391075,0.0000327261,0.0001790057,0.01139419,0.00007915705,0.0002916704,0.0000781511,0.0006682843,0.009483071,0.01960002,0.05601002,0.9020446],"study_design_scores_gemma":[0.00001661879,0.00003710692,0.0004680621,0.001055645,0.0000526211,0.0004565918,0.00005661556,0.0001278443,0.001589859,0.005525182,0.9905934,0.00002042427],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001845471,0.9971229,0.000351248,0.0006579476,0.0005757802,0.000003291307,0.00001977047,0.00001394336,0.001070493],"genre_scores_gemma":[0.000945675,0.9965076,0.0002387724,0.0005479767,0.000437812,0.000004299506,0.00003573444,0.000003246118,0.001278892],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002604452,"threshold_uncertainty_score":0.008712769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08379353042007048,"score_gpt":0.3637489456330353,"score_spread":0.2799554152129648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}