{"id":"W4412090238","doi":"10.1128/mbio.01196-25","title":"Auto-aggregation in <i>Streptococcus intermedius</i> is driven by the Pel polysaccharide","year":2025,"lang":"en","type":"article","venue":"mBio","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; McGill University; McMaster University; University of Toronto; Institute of Infection and Immunity; Hospital for Sick Children","funders":"Canadian Glycomics Network; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Hospital for Sick Children; Canada Research Chairs; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada; National Institutes of Health; Cystic Fibrosis Foundation","keywords":"Biofilm; Microbiology; Streptococcus intermedius; Biology; Gene; Mutant; Operon; Pseudomonas aeruginosa; Phenotype; Complementation; Gene cluster; Bacteria; Genetics; Streptococcus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001087565,0.0002876211,0.0001589286,0.0002084094,0.0001283564,0.0003044882,0.0001373099,0.0001614596,0.0008096703],"category_scores_gemma":[0.0001728527,0.00009800179,0.0002251208,0.0001715588,0.0001654012,0.0001104639,0.0003676954,0.0004127194,0.0002766024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002293164,"about_ca_system_score_gemma":0.000166787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001639361,"about_ca_topic_score_gemma":0.000910439,"domain_scores_codex":[0.9998127,0.00002678413,0.00001906527,0.00003262917,0.00007082184,0.000038061],"domain_scores_gemma":[0.9998565,0.00001763887,0.00005735792,0.00001734066,0.00002161557,0.00002956618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004989823,0.0000170792,0.0008562159,0.00001297148,0.000002975878,0.0000435711,0.00001581933,0.00002936226,0.9983023,0.00003896439,0.00003232786,0.0005985],"study_design_scores_gemma":[0.000007805918,0.0002914359,0.04255649,0.00001166237,0.00002134704,0.0008007111,0.0001514975,0.00237013,0.9518268,0.00009545017,0.00185709,0.000009723149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980441,0.0001642431,0.0007496846,0.00004123485,0.000006970763,0.00001158245,0.0002849911,0.00003850254,0.0006586836],"genre_scores_gemma":[0.9977842,0.00006217174,0.0008126429,0.00002777916,0.000003056277,0.000008770084,0.0004848303,0.00001108626,0.0008054992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001639361,"threshold_uncertainty_score":0.003259659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009605757019654455,"score_gpt":0.2902171223590677,"score_spread":0.2806113653394133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}