{"id":"W4412094609","doi":"10.1007/s00467-025-06852-9","title":"Nephrotoxicity of immunotherapy and targeted therapies used to treat paediatric cancer","year":2025,"lang":"en","type":"article","venue":"Pediatric Nephrology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Nephrotoxicity; Nephrology; Immunotherapy; Kidney cancer; Internal medicine; Cancer; Oncology; Cancer immunotherapy; Intensive care medicine; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003647924,0.0003364219,0.0007052347,0.0008013025,0.0002222899,0.00001423741,0.000363995,0.0004249742,0.0009099878],"category_scores_gemma":[0.00008259904,0.0002917805,0.0001517048,0.0009637007,0.0002772772,0.00009015714,0.0001246639,0.0003003684,0.00005401987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004512459,"about_ca_system_score_gemma":0.0002208898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005423347,"about_ca_topic_score_gemma":0.00003701223,"domain_scores_codex":[0.9978452,0.0005346445,0.0005768572,0.0004393847,0.00004881631,0.0005551092],"domain_scores_gemma":[0.9985089,0.0007047702,0.0002029024,0.0004423343,0.0001146391,0.00002650305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00309439,0.0002234464,0.05183852,0.00006242565,0.0004307521,0.00000222694,0.001587236,0.000009012339,0.9037385,0.0004791397,0.006610931,0.03192344],"study_design_scores_gemma":[0.01090072,0.001781953,0.4133464,0.00002927445,0.0005028587,0.00003715573,0.0003839816,0.000004468962,0.3234385,0.001108279,0.2475648,0.0009016759],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8487344,0.148167,0.0002707274,0.001366827,0.0006112633,0.0005986706,0.00004985276,0.00008369767,0.0001175004],"genre_scores_gemma":[0.9773173,0.01746112,0.0001445884,0.002211766,0.00009264721,0.0002241498,0.00001772197,0.00003004717,0.002500647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5802999,"threshold_uncertainty_score":0.9999534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009565091363411053,"score_gpt":0.260299783484215,"score_spread":0.250734692120804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}