{"id":"W4412098036","doi":"10.17504/protocols.io.j8nlkr7x6v5r/v1","title":"Isothermal Titration Calorimetry (ITC) v1","year":2025,"lang":"en","type":"preprint","venue":"","topic":"thermodynamics and calorimetric analyses","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Isothermal titration calorimetry; Calorimetry; Isothermal process; Titration; Thermodynamics; Materials science; Chemistry; Physical chemistry; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001000442,0.000327012,0.0003898577,0.0001928912,0.00006840251,0.0001021073,0.0004949595,0.0006283431,0.005504587],"category_scores_gemma":[0.00005578385,0.000304489,0.0003229182,0.0002250433,0.00003950398,0.00003596679,0.0004671038,0.0006934508,0.0001085725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001859248,"about_ca_system_score_gemma":0.0002622454,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502486,"about_ca_topic_score_gemma":0.00005865162,"domain_scores_codex":[0.9985217,0.00001536339,0.0003791448,0.0005460445,0.0002857496,0.0002520063],"domain_scores_gemma":[0.9988369,0.00008808222,0.0001626717,0.000734949,0.000104413,0.00007298659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006133572,0.002943714,0.02275734,0.01019157,0.009749036,0.0002031582,0.001064221,0.009463239,0.1658208,0.2422187,0.0834589,0.451516],"study_design_scores_gemma":[0.004616792,0.0001119277,0.005030645,0.002029991,0.004308636,0.00002293375,0.00131609,0.3696844,0.3463238,0.07927099,0.1780382,0.009245574],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.05875656,0.001138161,0.03456278,0.0001351853,0.0007329615,0.00009165314,0.0002567313,0.0003333064,0.9039927],"genre_scores_gemma":[0.8668849,0.0002090961,0.001476046,0.0002254972,0.0007073059,0.00003054328,0.0004266404,0.00003473754,0.1300052],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.8081284,"threshold_uncertainty_score":0.9999407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01594799220875248,"score_gpt":0.271266480409768,"score_spread":0.2553184882010155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}