{"id":"W4412098527","doi":"10.1111/boc.70024","title":"The Nuclear Envelope Proteins Esc1 and Mps3 Differentially Impact Sterol Gradients in Budding Yeast","year":2025,"lang":"en","type":"article","venue":"Biology of the Cell","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Biology; Budding yeast; Envelope (radar); Yeast; Sterol; Saccharomyces cerevisiae; Cell biology; Budding; Nuclear pore; Biochemistry; Aerospace engineering; Engineering; Cholesterol; Nucleus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006013825,0.0002955297,0.0002168259,0.0001726354,0.0001298717,0.0003403046,0.0001993958,0.0002092088,0.0008081137],"category_scores_gemma":[0.00006780904,0.0001917333,0.0001988099,0.0001572301,0.0001645635,0.0001370079,0.0003248602,0.0003050353,0.0003903589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000375225,"about_ca_system_score_gemma":0.0001453925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001846877,"about_ca_topic_score_gemma":0.001940133,"domain_scores_codex":[0.9999241,0.000009110468,0.000009736149,0.00001376117,0.00002837103,0.00001496475],"domain_scores_gemma":[0.9999206,0.00001224445,0.00002710304,0.00000888396,0.00001151276,0.00001959527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004457228,0.000003320299,0.0001161672,0.000009508938,0.000002311115,0.00002808432,0.000008272782,0.0000419466,0.9994774,0.00002686288,0.00000918833,0.0002324036],"study_design_scores_gemma":[0.000006928588,0.00005578414,0.006319879,0.000004086982,0.000008326843,0.000122421,0.00007274451,0.0007890734,0.991671,0.00003273384,0.0009117438,0.000005366016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977314,0.000299033,0.0008088219,0.00003087077,0.000005883103,0.000009057037,0.0005518735,0.00005176892,0.000511404],"genre_scores_gemma":[0.9957792,0.0002687365,0.0008587611,0.00002842791,0.000001392948,0.00001378447,0.0007049359,0.0000504259,0.00229431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001846877,"threshold_uncertainty_score":0.003672183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004413407681572627,"score_gpt":0.212758824626993,"score_spread":0.2083454169454204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}