{"id":"W4412156652","doi":"10.1007/s40119-025-00421-9","title":"Survival in a Contemporary, Real-World Cohort of Patients with Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis: An Analysis from THAOS","year":2025,"lang":"en","type":"article","venue":"Cardiology and Therapy","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"VA Greater Los Angeles Healthcare System; School of Medicine, Vanderbilt University; RWTH Aachen University; National Taiwan University; Universitair Medisch Centrum Groningen; National Institute of Diabetes and Digestive and Kidney Diseases; National Taiwan University Hospital; Universiti Malaya; University of Alberta; King Faisal Specialist Hospital and Research Centre; University of Colorado Denver; Universität Heidelberg; Pfizer; Medical Center, University of Pittsburgh; Samsung; Centre Hospitalier Universitaire de Toulouse; University of Pittsburgh; Cleveland Clinic; Sungkyunkwan University; Yale University; Vanderbilt University","keywords":"Medicine; Transthyretin; Internal medicine; Cohort; Amyloidosis; Population; Cohort study; Incidence (geometry); Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008876015,0.0003300599,0.0006016017,0.0007776109,0.0005670367,0.0008809385,0.0004147122,0.0005371289,0.001033119],"category_scores_gemma":[0.00159355,0.0002729659,0.0008349785,0.001041691,0.0003812808,0.0006664901,0.0008233057,0.0007618716,0.0002435352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000488046,"about_ca_system_score_gemma":0.0004587712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004352182,"about_ca_topic_score_gemma":0.004252929,"domain_scores_codex":[0.999419,0.0001279764,0.00005919734,0.0001988575,0.00009234038,0.0001027039],"domain_scores_gemma":[0.9985059,0.0002343558,0.0006041548,0.0001546784,0.000158157,0.0003426619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005701069,0.00005244941,0.9981382,0.00000814674,0.0001108173,0.0000907521,0.00009433262,0.00005351928,0.0001444406,0.00001486384,0.0001337904,0.0005886055],"study_design_scores_gemma":[0.00007609647,0.000417014,0.9977903,0.000008786865,0.00009970339,0.0004740733,0.0004191257,0.0003867189,0.00004500516,0.00003076194,0.0002429026,0.000009491619],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993982,0.00008786203,0.00002959434,0.0000212158,0.000003118885,0.000005712704,0.000349607,0.000001322956,0.0001033367],"genre_scores_gemma":[0.9987783,0.00007378017,0.00003266164,0.0000302395,0.0000128897,0.00001245163,0.00101191,0.000002007896,0.00004589774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004352182,"threshold_uncertainty_score":0.0086537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009742529089259655,"score_gpt":0.2486790780068405,"score_spread":0.2389365489175808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}