{"id":"W4412156841","doi":"10.1080/09513590.2025.2526560","title":"Targeting vasomotor symptoms with the new drug fezolinetant – an expert overview","year":2025,"lang":"en","type":"review","venue":"Gynecological Endocrinology","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Astellas Foundation for Research on Metabolic Disorders; Astellas Pharma; Astellas Pharma Canada","keywords":"Vasomotor; Drug; Medicine; Pharmacology; Intensive care medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002206312,0.0007656901,0.003340537,0.0001427901,0.0003118684,0.00002253256,0.0005447855,0.0002527144,0.0004900014],"category_scores_gemma":[0.0008035189,0.0003112065,0.0005473617,0.0004693464,0.0005435746,0.00004504215,0.0005272307,0.00118512,0.0001186382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001641314,"about_ca_system_score_gemma":0.0007127227,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005541212,"about_ca_topic_score_gemma":0.00003210329,"domain_scores_codex":[0.9963267,0.0005147688,0.0006840471,0.001236129,0.0002935075,0.0009448643],"domain_scores_gemma":[0.9973419,0.001178041,0.000302511,0.0007905154,0.0001586983,0.0002283622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006631093,0.0002724193,0.00002768337,0.003331432,0.001010964,0.0006873811,0.0000905479,8.619064e-7,0.000001377129,0.002107572,0.01120409,0.9811994],"study_design_scores_gemma":[0.0006651821,0.0009380334,0.0002187238,0.001735982,0.001313357,0.0004772132,0.0001454047,0.00000141962,0.000001697563,0.00009823473,0.9940298,0.0003749952],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006366464,0.9902177,0.00002283909,0.004374489,0.0004960205,0.001949467,0.00001649766,0.0002054851,0.002653774],"genre_scores_gemma":[0.00008252513,0.9884159,0.0003546114,0.001240358,0.001271679,0.0004967555,0.0001018083,0.0000410965,0.007995248],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9828256,"threshold_uncertainty_score":0.999934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04869777701113861,"score_gpt":0.3541745581446406,"score_spread":0.305476781133502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}