{"id":"W4412191252","doi":"10.1002/ueg2.70050","title":"Assessment of PredictSURE IBD Assay in a Multinational Cohort of Patients With Inflammatory Bowel Disease","year":2025,"lang":"en","type":"article","venue":"United European Gastroenterology Journal","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; NIHR Cambridge Biomedical Research Centre; Medical Research Council; Vlaamse regering; National Institutes of Health; Leona M. and Harry B. Helmsley Charitable Trust; Cancer Research UK; Fonds Wetenschappelijk Onderzoek; Crohn's and Colitis Foundation; Lister Institute of Preventive Medicine; Wellcome Trust; Francis Crick Institute; KU Leuven; National Institute for Health and Care Research","keywords":"Medicine; Inflammatory bowel disease; Internal medicine; Ulcerative colitis; Interquartile range; Cohort; Biomarker; Gastroenterology; Corticosteroid; Crohn's disease; Concomitant; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002334164,0.0003760169,0.000384871,0.000520933,0.000327348,0.0006791073,0.0003947393,0.0003897013,0.0007051821],"category_scores_gemma":[0.004737064,0.0001980631,0.0003189924,0.0004536783,0.000316303,0.0004250809,0.0006424935,0.0005185651,0.0002029266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002620221,"about_ca_system_score_gemma":0.0001797493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001502482,"about_ca_topic_score_gemma":0.001705284,"domain_scores_codex":[0.9989323,0.0003484897,0.0001089817,0.000280861,0.0002239606,0.0001053381],"domain_scores_gemma":[0.9967517,0.0007014712,0.001464717,0.0005171648,0.0002859797,0.0002789584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001571569,0.00001689598,0.9982105,0.000002945467,0.00001460975,0.00002222362,0.00002600193,0.00003847798,0.0004859788,0.000004062385,0.0000278519,0.0009932753],"study_design_scores_gemma":[0.00001119045,0.0003448626,0.9978985,0.000003314747,0.00003336686,0.0004128614,0.00006152671,0.0005882641,0.0004296727,0.000009225604,0.0002033915,0.000003771495],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994912,0.00008766245,0.0001299171,0.00001587547,0.000003321953,0.00000731215,0.0001321303,0.000004132114,0.0001284446],"genre_scores_gemma":[0.9992115,0.00003711828,0.0002694734,0.00002286545,0.000007493706,0.00001185393,0.0003699363,0.000001696423,0.0000680401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002334164,"threshold_uncertainty_score":0.01234436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002660668197629939,"score_gpt":0.2132544381039822,"score_spread":0.2105937699063523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}