{"id":"W4412191252","doi":"10.1002/ueg2.70050","title":"Assessment of PredictSURE IBD Assay in a Multinational Cohort of Patients With Inflammatory Bowel Disease","year":2025,"lang":"en","type":"article","venue":"United European Gastroenterology Journal","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; NIHR Cambridge Biomedical Research Centre; Medical Research Council; Vlaamse regering; National Institutes of Health; Leona M. and Harry B. Helmsley Charitable Trust; Cancer Research UK; Fonds Wetenschappelijk Onderzoek; Crohn's and Colitis Foundation; Lister Institute of Preventive Medicine; Wellcome Trust; Francis Crick Institute; KU Leuven; National Institute for Health and Care Research","keywords":"Medicine; Inflammatory bowel disease; Internal medicine; Ulcerative colitis; Interquartile range; Cohort; Biomarker; Gastroenterology; Corticosteroid; Crohn's disease; Concomitant; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007107216,0.0001685296,0.0001404924,0.0004560534,0.00004955855,0.000009629483,0.0002789581,0.00004906213,0.00002329255],"category_scores_gemma":[0.0001607989,0.0001512394,0.00008474506,0.00008528885,0.0002105461,0.00001069231,0.0001380341,0.0002560058,6.530281e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003482964,"about_ca_system_score_gemma":0.0002023942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":5.747519e-7,"about_ca_topic_score_gemma":0.000008911031,"domain_scores_codex":[0.9979196,0.0008259673,0.0005511833,0.0002178566,0.0002391757,0.0002462849],"domain_scores_gemma":[0.9987128,0.00001571634,0.0003765261,0.0002659188,0.0004866537,0.0001424273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001872958,0.0004085275,0.9918798,0.00005724205,0.0002013109,0.0001212261,0.00001509439,0.004188424,0.0008587958,0.00006400251,0.0003067201,0.00002584818],"study_design_scores_gemma":[0.003845073,0.0002990463,0.9949028,0.0001117797,0.00006876451,0.000005383356,0.00001790687,0.0004917655,0.00002820745,0.000006562557,0.0001530856,0.00006966379],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967365,0.00001620717,0.002075222,0.00004333477,0.00009782736,0.0002310998,0.0001000078,0.000005615271,0.0006941389],"genre_scores_gemma":[0.9988918,0.00001327043,0.0004438284,0.0002310242,0.00004053926,0.000005766728,0.0002872133,0.00002094173,0.00006566734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003696659,"threshold_uncertainty_score":0.6167365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002660668197629939,"score_gpt":0.2132544381039822,"score_spread":0.2105937699063523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}