{"id":"W4412356041","doi":"10.1002/mdc3.70226","title":"How Do I Do a Skin Punch Biopsy for Research and Diagnostic Purposes in Parkinson's Disease and Atypical Parkinsonism?","year":2025,"lang":"en","type":"article","venue":"Movement Disorders Clinical Practice","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Parkinson's Clinic of Eastern Toronto & Movement Disorders Centre","funders":"","keywords":"Parkinsonism; Parkinson's disease; Medicine; Dermatology; Disease; Skin biopsy; Biopsy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02741321,0.0004849244,0.001589293,0.002195252,0.002249482,0.004249974,0.0024217,0.007243087,0.007523744],"category_scores_gemma":[0.1127201,0.0007111084,0.0009564374,0.001083426,0.003605082,0.009139333,0.001397122,0.005585124,0.008788495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001400526,"about_ca_system_score_gemma":0.004027375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005104882,"about_ca_topic_score_gemma":0.01079748,"domain_scores_codex":[0.9917788,0.004306163,0.001039351,0.0007239357,0.00134299,0.0008087219],"domain_scores_gemma":[0.9623021,0.01543241,0.004149452,0.003048177,0.009561327,0.005506529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00133922,0.0009624379,0.09868091,0.00197797,0.0002930463,0.02264107,0.008284248,0.0005937502,0.00334322,0.005671887,0.4662205,0.3899918],"study_design_scores_gemma":[0.0008230488,0.002090616,0.09411654,0.02247393,0.0005810676,0.1686248,0.06041482,0.003471843,0.005094633,0.08104447,0.5603157,0.0009485858],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.0708966,0.05818698,0.0308929,0.7371743,0.03779683,0.00174069,0.001173362,0.0006992746,0.06143917],"genre_scores_gemma":[0.4682581,0.06824084,0.1283178,0.2823272,0.03154967,0.00242608,0.001113301,0.0006655872,0.01710143],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.02741321,"threshold_uncertainty_score":0.1449766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06087101631928529,"score_gpt":0.4191978582387607,"score_spread":0.3583268419194754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}