{"id":"W4412363265","doi":"10.1016/j.celrep.2025.115976","title":"White-Brown switching controls phenotypic plasticity and virulence of Candida auris","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"LEO Fondet; Austrian Science Fund; ASEAN-European Academic University Network; European Society of Clinical Microbiology and Infectious Diseases; Canadian Institute for Advanced Research","keywords":"Biology; Virulence; Phenotypic switching; Candida auris; Morphogenesis; Phenotype; Adaptation (eye); Genetics; White (mutation); Gene; Fungal pathogen; Phenotypic plasticity; Antifungal drug; Fungus; Microbiology; Antifungal; Neuroscience; Botany","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007296669,0.0001711103,0.0001335139,0.0002294993,0.0001668232,0.0004374784,0.000130731,0.0001432484,0.0007610335],"category_scores_gemma":[0.0001780613,0.0000878493,0.00009987639,0.0001204609,0.0002386238,0.0001254237,0.0003781814,0.0002242996,0.0002097445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002420096,"about_ca_system_score_gemma":0.0001196912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006602892,"about_ca_topic_score_gemma":0.0009765979,"domain_scores_codex":[0.9998517,0.00002082406,0.000007758309,0.00003657749,0.00003169321,0.00005139418],"domain_scores_gemma":[0.9999027,0.00001590259,0.00003086651,0.00001402628,0.0000107882,0.00002562922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006914027,0.000007309089,0.001051731,0.000004841224,0.0000010184,0.0000273737,0.00001806012,0.00004825692,0.9973155,0.0001057293,0.00002126595,0.001329681],"study_design_scores_gemma":[0.00001310986,0.0001806787,0.1126435,0.00000833167,0.00001338315,0.0006028197,0.0003294457,0.004942141,0.8783687,0.00036041,0.002519919,0.00001748384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977345,0.0002521608,0.0008910345,0.00003287425,0.000005536525,0.000004906353,0.00009285196,0.00002973512,0.0009563157],"genre_scores_gemma":[0.9991276,0.00008258148,0.000230985,0.00001502695,0.000002402258,0.000004669952,0.00006434796,0.000009134387,0.0004633608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007610335,"threshold_uncertainty_score":0.002545893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007099587703218198,"score_gpt":0.2477901645748353,"score_spread":0.2406905768716171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}