{"id":"W4412366126","doi":"10.1093/gbe/evaf142","title":"From macro to micro: De novo genomes of Aedes mosquitoes enable comparative genomics among close and distant relatives","year":2025,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Genome; Synteny; Comparative genomics; Aedes aegypti; Evolutionary biology; Genetics; Reference genome; Genomics; Yellow fever; Genome evolution; Gene; Ecology; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003570722,0.0004270884,0.0003767032,0.0004963864,0.0003462975,0.0008191984,0.0003342301,0.0003033766,0.002123829],"category_scores_gemma":[0.001036945,0.0003141994,0.0004146737,0.0007750113,0.0001613792,0.0006739178,0.0006027179,0.0009303139,0.001015077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004114211,"about_ca_system_score_gemma":0.000428991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001728298,"about_ca_topic_score_gemma":0.004542138,"domain_scores_codex":[0.9998564,0.00001740561,0.000009583421,0.00007015337,0.0000291309,0.0000174867],"domain_scores_gemma":[0.9994837,0.0001799877,0.00008422276,0.0001005854,0.00009508902,0.00005635112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005544874,0.00006539782,0.008154399,0.0007121205,0.0001222621,0.0005611771,0.0006362324,0.003422481,0.9167809,0.004484374,0.003652802,0.06085333],"study_design_scores_gemma":[0.0001610156,0.0006511758,0.1009445,0.0003303913,0.0003700468,0.002145804,0.000684584,0.0206692,0.459788,0.00893647,0.4051988,0.0001200002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7103149,0.005360208,0.1926686,0.001099008,0.0003557995,0.0002787558,0.0740752,0.003283872,0.01256367],"genre_scores_gemma":[0.6229501,0.003960555,0.2427473,0.0005339669,0.0001029042,0.0002865922,0.1224156,0.001758407,0.005244599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002123829,"threshold_uncertainty_score":0.007104933,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008244722258590409,"score_gpt":0.2789959758456158,"score_spread":0.2707512535870253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}