{"id":"W4412387662","doi":"10.1080/13696998.2025.2530862","title":"Cost-effectiveness analysis of pembrolizumab as an adjuvant treatment of early-stage non-small cell lung cancer following complete resection and platinum-based chemotherapy in Canada","year":2025,"lang":"en","type":"article","venue":"Journal of Medical Economics","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Merck Canada Inc. (Canada)","funders":"","keywords":"Medicine; Pembrolizumab; Stage (stratigraphy); Chemotherapy; Oncology; Lung cancer; Adjuvant chemotherapy; Adjuvant; Cancer; Internal medicine; Resection; Surgery; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005699927,0.0001219126,0.0008563122,0.0003751096,0.00002268635,0.000007054364,0.00009156443,0.00009415429,0.0001087041],"category_scores_gemma":[0.00002264359,0.0001002871,0.0002286943,0.0002734273,0.00004835496,0.00004675845,0.000007948622,0.0001374307,1.827707e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00159165,"about_ca_system_score_gemma":0.003906207,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.4934427,"about_ca_topic_score_gemma":0.5400901,"domain_scores_codex":[0.9987635,0.00007878854,0.0006796379,0.0001414249,0.0001986461,0.0001380046],"domain_scores_gemma":[0.9990056,0.0002513759,0.0004103191,0.0001351342,0.00006244024,0.0001351376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02067206,0.0005322053,0.9079855,0.0004090907,0.004686347,0.00009956548,0.000717509,0.005711133,0.004297553,0.000008753331,0.00002458631,0.0548557],"study_design_scores_gemma":[0.03044326,0.001722793,0.8639997,0.000747559,0.001203327,0.000007356284,0.0005492263,0.08563504,0.01489507,0.000006173069,0.0006628754,0.0001276046],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974524,0.001190684,0.0002532105,0.0004726223,0.0002286976,0.0003082892,0.00003010249,0.000001252463,0.00006274346],"genre_scores_gemma":[0.9976982,0.001889417,0.00007120337,0.0002628161,0.00003246438,0.00001006834,0.000007264209,0.000009074674,0.00001950621],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07992391,"threshold_uncertainty_score":0.6929443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02408850010101859,"score_gpt":0.3212812795561362,"score_spread":0.2971927794551176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}