{"id":"W4412391764","doi":"10.1016/j.molmed.2025.06.010","title":"ILC2s in cancer: good, bad, or stay tuned?","year":2025,"lang":"en","type":"article","venue":"Trends in Molecular Medicine","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Children's Hospital; Alberta Cancer Foundation; Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Innate lymphoid cell; Cancer; Medicine; Immunotherapy; Immunity; Breast cancer; Immunology; Ovarian cancer; Oncology; Cancer research; Internal medicine; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000332841,0.0002380626,0.0005163313,0.0007176715,0.00005371223,0.000003393432,0.0002828755,0.0002763765,0.001601268],"category_scores_gemma":[0.0001700587,0.0001795724,0.00005194885,0.001204737,0.0002640953,0.00003684173,0.00008102936,0.0004847262,0.00005278029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00012147,"about_ca_system_score_gemma":0.0001531567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001712401,"about_ca_topic_score_gemma":0.003241607,"domain_scores_codex":[0.9983911,0.0002113197,0.0004457707,0.0004008622,0.00006021413,0.0004907632],"domain_scores_gemma":[0.999394,0.00008870349,0.00006846895,0.0003830483,0.0000393105,0.00002649627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008107045,0.0004164162,0.01359016,0.0001248961,0.0002754688,0.0008016393,0.002639001,0.00003317877,0.7492155,0.007612462,0.02654063,0.1979399],"study_design_scores_gemma":[0.01568225,0.0008735107,0.05498601,0.001145715,0.0001582299,0.00005123523,0.00102914,0.00001870748,0.1381026,0.0008591064,0.7865211,0.0005724979],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8160791,0.03063537,0.0008833574,0.007056318,0.004107717,0.0004476735,0.0004775631,0.0001861744,0.1401267],"genre_scores_gemma":[0.9731812,0.0007843357,0.00007771925,0.001859028,0.00004605902,0.0000683662,0.0001726493,0.0000202746,0.02379031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7599804,"threshold_uncertainty_score":0.9993114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01733184760902327,"score_gpt":0.3144585603039406,"score_spread":0.2971267126949173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}