{"id":"W4412395554","doi":"10.7554/elife.97100.3.sa2","title":"eLife Assessment: Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Parvalbumin; Neuroscience; Synaptic membrane; Auditory cortex; Cortex (anatomy); Chemistry; Biology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.0002587124,0.0004941236,0.0004591503,0.0007312748,0.0006081214,0.0007193341,0.0008877914,0.0009955813,0.0111002],"category_scores_gemma":[0.0001924235,0.000453654,0.0003873009,0.0003680981,0.0005683898,0.0004874399,0.001093113,0.001731359,0.004489725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000632774,"about_ca_system_score_gemma":0.0005038216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0014456,"about_ca_topic_score_gemma":0.003711484,"domain_scores_codex":[0.9995133,0.00001633083,0.00003554065,0.0001280313,0.0001862573,0.000120639],"domain_scores_gemma":[0.9996587,0.0000253973,0.00009063016,0.00002407215,0.00005135613,0.000149785],"domain_codex":null,"domain_gemma":"evaluation","domain_candidate":"evaluation","domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000185709,0.00003133681,0.0004141806,0.0001204761,0.000009369519,0.0002385736,0.00006895042,0.000132263,0.9935427,0.0004636047,0.0007842773,0.004008626],"study_design_scores_gemma":[0.0001060749,0.0001435672,0.01949623,0.00006159344,0.00003953734,0.0008768614,0.0002844688,0.004945733,0.9450082,0.0004482508,0.02857053,0.00001888481],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.9232277,0.005817561,0.03097855,0.003010114,0.0005836463,0.0001335667,0.008575683,0.002664802,0.02500847],"genre_scores_gemma":[0.8898804,0.003258412,0.02361942,0.0008881487,0.00009478057,0.0002534537,0.006252134,0.0009373126,0.07481606],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.9997413,"threshold_uncertainty_score":0.03713387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03891441638916405,"score_gpt":0.3767825197494486,"score_spread":0.3378681033602846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}