{"id":"W4412443185","doi":"10.1016/j.jval.2025.04.1898","title":"EE299 Cost Per PFS-Based Responder for TKI-Naive Patients Receiving Repotrectinib or Entrectinib in ROS1 Fusion Positive Non-Small Cell Lung Cancer (NSCLC) in the United States (US)","year":2025,"lang":"en","type":"article","venue":"Value in Health","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver Coastal Health","funders":"","keywords":"Medicine; ROS1; Oncology; Internal medicine; Lung cancer; Cancer; Adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005012397,0.0002386964,0.0003604397,0.0003593211,0.0001487657,0.0007062669,0.0003584025,0.0004812285,0.006999455],"category_scores_gemma":[0.00171575,0.0001421833,0.001908366,0.0004509148,0.0001593126,0.0005104038,0.0003875408,0.0009854743,0.0007178409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002273919,"about_ca_system_score_gemma":0.001419638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01166674,"about_ca_topic_score_gemma":0.01418922,"domain_scores_codex":[0.9995659,0.0001521449,0.00004385154,0.00006434439,0.00008353532,0.00009022215],"domain_scores_gemma":[0.9995067,0.0001660007,0.0001613209,0.00001266605,0.00003343116,0.0001197553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0468661,0.001801145,0.2868205,0.001720216,0.003955813,0.002007781,0.0001570669,0.05522194,0.006667732,0.008033806,0.08943936,0.4973085],"study_design_scores_gemma":[0.007938687,0.01491417,0.8399872,0.0007249166,0.004799764,0.004775065,0.0007165756,0.05529015,0.004374939,0.005403186,0.06095521,0.0001202496],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9361246,0.007117263,0.001544887,0.008320919,0.0003036745,0.0002767681,0.02566524,0.0002531671,0.02039348],"genre_scores_gemma":[0.986264,0.001561201,0.0003697281,0.001286856,0.000092322,0.00006658004,0.005454432,0.000017974,0.004887042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01166674,"threshold_uncertainty_score":0.02341557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02678779157051242,"score_gpt":0.3707376201956284,"score_spread":0.343949828625116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}