{"id":"W4412463040","doi":"10.1016/j.jtct.2025.07.010","title":"Effect of Anti-Thymocyte Globulin and Post-Transplant Cyclophosphamide on Graft-Versus-Host Disease Outcomes in Female Donor-to-Male Recipient Matched Unrelated Donor Allogeneic Stem Cell Transplantation for Acute Leukemia","year":2025,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; U.S. Public Health Service; Office of Naval Research; Health Resources and Services Administration; National Cancer Institute; Medical College of Wisconsin; National Marrow Donor Program","keywords":"Anti-thymocyte globulin; Cyclophosphamide; Transplantation; Globulin; Thymocyte; Immunology; Leukemia; Stem cell; Medicine; Oncology; Internal medicine; Biology; T cell; Chemotherapy; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005113683,0.0005170562,0.0008961073,0.0004642743,0.0001249172,0.00003450456,0.0001283782,0.0002456436,0.000023332],"category_scores_gemma":[0.000004580451,0.000442593,0.000208527,0.0003822595,0.00008958452,0.0001159038,0.000004416965,0.000213543,0.000007632366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001068504,"about_ca_system_score_gemma":0.0001285357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001327632,"about_ca_topic_score_gemma":0.00005030836,"domain_scores_codex":[0.9974568,0.0002305702,0.0008294955,0.0007050253,0.0003500252,0.0004280781],"domain_scores_gemma":[0.9984359,0.0007322684,0.0001532569,0.0002991937,0.00009205591,0.000287335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.1077452,0.0004938897,0.243011,0.006862125,0.0007944615,0.0005785295,0.008068714,0.0005286669,0.6245347,0.0003209353,0.000005640913,0.007056153],"study_design_scores_gemma":[0.02764131,0.00222862,0.3410323,0.001127852,0.001591724,0.00003155619,0.0001909646,0.0002006442,0.6254774,0.00001112821,0.00004811839,0.0004183282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888832,0.001198628,0.004960497,0.0004274691,0.0002881391,0.003338412,0.0006731906,0.00007633441,0.0001541388],"genre_scores_gemma":[0.9819649,0.01557849,0.0003764981,0.0003798552,0.00001465735,0.0002534839,0.001063953,0.0000542406,0.0003139401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09802128,"threshold_uncertainty_score":0.9998026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009994106245814273,"score_gpt":0.271785113986954,"score_spread":0.2617910077411397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}