{"id":"W4412483696","doi":"10.1021/acsomega.5c03650","title":"Cerebrospinal Fluid p-Tau181/Amyloid Beta 42 Ratio Identifies Lymphatic-Venous Anastomosis Patients Who Respond to and Benefit from the Surgery for Relief of Cognitive Impairment with a Diagnostic Accuracy of 0.744","year":2025,"lang":"en","type":"article","venue":"ACS Omega","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Research Grants Council, University Grants Committee; State Administration of Traditional Chinese Medicine of the People's Republic of China; Department of Science and Technology of Shandong Province","keywords":"Cerebrospinal fluid; Medicine; Cognitive impairment; Anastomosis; Glymphatic system; Surgery; Lymphatic system; Anesthesia; Internal medicine; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008175252,0.0005703581,0.0004120427,0.001555977,0.0003098507,0.0007254764,0.0003066106,0.0006229844,0.002905397],"category_scores_gemma":[0.002350203,0.0002367104,0.0004210763,0.0004032053,0.0003198235,0.0004850559,0.0004223817,0.0003034371,0.0009667653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001422399,"about_ca_system_score_gemma":0.0001619585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007106619,"about_ca_topic_score_gemma":0.00100559,"domain_scores_codex":[0.9996909,0.0000670205,0.00004690946,0.00005917393,0.00007365235,0.0000623931],"domain_scores_gemma":[0.9992104,0.0002334433,0.0002118516,0.00004849472,0.0001497571,0.0001461021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009542369,0.0001326397,0.9848288,0.00003654693,0.00006916827,0.001262945,0.0001111467,0.00009590534,0.004407052,0.00003403921,0.0004776705,0.00758977],"study_design_scores_gemma":[0.00004445871,0.0005461001,0.990803,0.00002212119,0.00009165586,0.004653682,0.0002815826,0.001173489,0.001596075,0.00009973203,0.0006762338,0.00001189369],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978569,0.0003398768,0.000199946,0.00004541111,0.00001825117,0.00001728497,0.00009569079,0.00001987819,0.001406869],"genre_scores_gemma":[0.9991529,0.00009672554,0.0002366534,0.00001924205,0.00001601912,0.00001039365,0.0001368032,0.000002695002,0.0003286554],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002905397,"threshold_uncertainty_score":0.009719551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009286188784692829,"score_gpt":0.2520389420156725,"score_spread":0.2427527532309796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}