{"id":"W4412491112","doi":"10.1371/journal.ppat.1013347","title":"Profiling miRNA changes in Epstein-Barr virus lytic infection identifies a function for BZLF1 in upregulating miRNAs from the DLK1-DIO3 locus","year":2025,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"BZLF1; microRNA; Lytic cycle; Biology; Locus (genetics); Epstein–Barr virus; Virology; Virus; Genetics; Gene; Herpesviridae; Viral disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001547039,0.0001882806,0.0002546048,0.0002538709,0.0001223249,0.0002878445,0.0001102846,0.0002075993,0.0007493939],"category_scores_gemma":[0.0002101446,0.0001560628,0.0002520959,0.0002103713,0.0001357722,0.0002237421,0.0002230667,0.0003828183,0.000403365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002093503,"about_ca_system_score_gemma":0.0001351355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004551963,"about_ca_topic_score_gemma":0.0005796076,"domain_scores_codex":[0.9998609,0.00001159593,0.00001156703,0.00004928511,0.00003615258,0.00003057102],"domain_scores_gemma":[0.9998789,0.00002698755,0.00003837127,0.00001265431,0.00001782426,0.00002524338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001084256,0.000003636462,0.0009696862,0.00001640047,0.000002806877,0.00001618324,0.00001588887,0.00001565717,0.9980094,0.00001245314,0.000008755665,0.0008206601],"study_design_scores_gemma":[0.00001647378,0.000154152,0.08956283,0.000007730274,0.00003328853,0.0003279456,0.0000665312,0.001208044,0.9064578,0.00008143028,0.002073198,0.0000106851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932668,0.00173246,0.003147928,0.00003518809,0.000009546637,0.00002135357,0.0009380516,0.00006963814,0.0007790237],"genre_scores_gemma":[0.9929901,0.0005445504,0.003701926,0.00005350642,0.000004517177,0.00003640722,0.001392528,0.00003580871,0.001240723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007493939,"threshold_uncertainty_score":0.002506912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02267913371142836,"score_gpt":0.2699307046656146,"score_spread":0.2472515709541862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}