{"id":"W4412493735","doi":"10.1164/rccm.202505-1235le","title":"Reply to Sun <i>et al.</i> : Neuromuscular Blockade Efficacy in High Elastance Acute Respiratory Distress Syndrome: Signal or Statistical Noise?","year":2025,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Hemodynamic Monitoring and Therapy","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto; Foothills Medical Centre; University of Calgary; Alberta Health Services","funders":"","keywords":"Medicine; ARDS; Neuromuscular Blockade; Elastance; Noise (video); SIGNAL (programming language); Blockade; Anesthesia; Internal medicine; Respiratory system; Lung","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008904096,0.0003264263,0.001183931,0.0004490516,0.00009912555,0.0000263904,0.0002186071,0.00006197751,0.00006637559],"category_scores_gemma":[0.001658205,0.0002344627,0.00009968197,0.0008248139,0.00104248,0.00009055951,0.00006106797,0.000973775,0.000002288077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001538829,"about_ca_system_score_gemma":0.000456346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006181456,"about_ca_topic_score_gemma":0.000007604865,"domain_scores_codex":[0.9967821,0.0004950249,0.001004112,0.0004826596,0.0007474167,0.0004886378],"domain_scores_gemma":[0.996843,0.001388813,0.0001561842,0.0004014913,0.0004413091,0.0007691684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03301796,0.002597807,0.1438962,0.00185727,0.001326451,0.09232688,0.004232427,0.0001567292,0.05280881,0.00690213,0.02551996,0.6353574],"study_design_scores_gemma":[0.02098359,0.06651857,0.4778168,0.009354661,0.001577775,0.002655063,0.007405877,0.00005101082,0.002482044,0.0003041885,0.4097373,0.001113192],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673482,0.002202615,0.004000369,0.02552367,0.0004428452,0.0002637924,0.00004896564,0.00002959373,0.0001399575],"genre_scores_gemma":[0.9285877,0.0001089241,0.0008224154,0.07018942,0.0002059704,0.00001233862,0.000004100002,0.00003310168,0.00003599648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6342442,"threshold_uncertainty_score":0.9561113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01198867000392135,"score_gpt":0.3328424576406248,"score_spread":0.3208537876367035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}