{"id":"W4412501589","doi":"10.1002/alz.70470","title":"Implications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies","year":2025,"lang":"en","type":"review","venue":"Alzheimer s & Dementia","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Movement Disorders","funders":"National Institute on Aging; Lewy Body Dementia Association; Demensförbundet","keywords":"Dementia with Lewy bodies; Disease; Neurodegeneration; Dementia; Medicine; Parkinson's disease; Neuroscience; Biomarker; Neurochemical; Synucleinopathies; Alpha-synuclein; Lewy body; Alzheimer's disease; Dopaminergic; Pathology; Psychology; Biology; Dopamine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01963066,0.001099321,0.00155113,0.002854636,0.004072075,0.009365057,0.003017355,0.006746402,0.003995706],"category_scores_gemma":[0.02472954,0.0004823715,0.001353223,0.001942697,0.03044149,0.01690712,0.007094893,0.0114717,0.0007882185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006945765,"about_ca_system_score_gemma":0.01117029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006405022,"about_ca_topic_score_gemma":0.009663154,"domain_scores_codex":[0.990404,0.005480267,0.0005763025,0.001217557,0.001492445,0.0008294756],"domain_scores_gemma":[0.982711,0.01044137,0.001279494,0.0008693106,0.002869523,0.001829288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003872501,0.0001985223,0.007847644,0.00193637,0.0001394658,0.001965326,0.01806019,0.0007232195,0.001103522,0.7353373,0.04524343,0.1870578],"study_design_scores_gemma":[0.0000439676,0.0001192473,0.00596858,0.003252425,0.0000889225,0.002180385,0.02436159,0.0005219161,0.000406105,0.7879918,0.1749559,0.0001092614],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.01119949,0.2634119,0.005826127,0.6931365,0.008968128,0.00004944126,0.0001422997,0.00004369801,0.01722235],"genre_scores_gemma":[0.4363776,0.2730145,0.01475168,0.2461314,0.02176011,0.0004252685,0.0003934017,0.0001270701,0.007019019],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01963066,"threshold_uncertainty_score":0.1038181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09505812595225878,"score_gpt":0.3374461292656454,"score_spread":0.2423880033133867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}