{"id":"W4412502479","doi":"10.20944/preprints202507.1434.v1","title":"Potential Vaccine or Antimicrobial Reagents: Simple Systems for Producing Lambda Display Particles (LDP) and Sheathed Lambda DNA Vaccine Particles (LDNAP)","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation","keywords":"Lambda; Simple (philosophy); DNA; DNA vaccination; Reagent; Physics; Virology; Chemistry; Biology; Genetics; Optics; Philosophy; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001343789,0.0005292517,0.0006931663,0.0001400584,0.0002513987,0.0001341531,0.0007234725,0.0005946222,0.00005526771],"category_scores_gemma":[0.001429149,0.000433198,0.0002394163,0.0001395665,0.0001200066,0.00001478397,0.00277325,0.000404621,0.00003316894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005487837,"about_ca_system_score_gemma":0.0003885509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002570666,"about_ca_topic_score_gemma":0.0001884786,"domain_scores_codex":[0.9961677,0.0001879284,0.001072581,0.001314888,0.0003886213,0.0008683145],"domain_scores_gemma":[0.9974467,0.00007978112,0.000344961,0.001377468,0.0004005153,0.0003505965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002603004,0.0006249587,0.09420007,0.004768869,0.000963881,0.00002008921,0.0006114429,0.001037989,0.8828607,0.00003841607,0.006161158,0.006109424],"study_design_scores_gemma":[0.004091477,0.0004749614,0.06154916,0.0006559218,0.0004160549,0.0000410012,0.0004093046,0.009800028,0.8906267,0.0003136704,0.030526,0.001095742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925534,0.000590142,0.002369517,0.000942515,0.000825145,0.002134149,0.0004352928,0.00006110199,0.00008870543],"genre_scores_gemma":[0.9925734,0.00254422,0.0007568585,0.0001959376,0.0008808488,0.0003202113,0.0007994295,0.00004941573,0.001879663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03265091,"threshold_uncertainty_score":0.999812,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05303827460397381,"score_gpt":0.3401152363800458,"score_spread":0.2870769617760719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}