{"id":"W4412502479","doi":"10.20944/preprints202507.1434.v1","title":"Potential Vaccine or Antimicrobial Reagents: Simple Systems for Producing Lambda Display Particles (LDP) and Sheathed Lambda DNA Vaccine Particles (LDNAP)","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Genetics, Bioinformatics, and Biomedical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation","keywords":"Lambda; Simple (philosophy); DNA; DNA vaccination; Reagent; Physics; Virology; Chemistry; Biology; Genetics; Optics; Philosophy; Physical chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006948896,0.0004702615,0.0003222149,0.0003636643,0.0002401977,0.0009124459,0.0004526864,0.0006938054,0.001073811],"category_scores_gemma":[0.0004052802,0.0002879037,0.000443086,0.0002044244,0.0004835851,0.0008259436,0.0005577272,0.0008281115,0.0007680279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005839006,"about_ca_system_score_gemma":0.0002437731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002616218,"about_ca_topic_score_gemma":0.0003344227,"domain_scores_codex":[0.9996182,0.00009747146,0.00002533096,0.00008307429,0.0001306521,0.00004529089],"domain_scores_gemma":[0.9998769,0.00003537628,0.00003082216,0.00001646685,0.00001695027,0.00002343873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005078595,0.00003544153,0.0002052203,0.0003285707,0.00001215778,0.0001128723,0.00008047135,0.0003235124,0.989809,0.002276266,0.0001398119,0.006625943],"study_design_scores_gemma":[0.00001970048,0.0004764315,0.0004739669,0.00003422081,0.00002529303,0.000448071,0.00003401832,0.001064337,0.9747581,0.0005222365,0.02212804,0.00001539001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7589173,0.02267133,0.2039318,0.0008774935,0.0003724233,0.000755553,0.0007722605,0.0009041104,0.01079762],"genre_scores_gemma":[0.8535429,0.008528703,0.1240307,0.0002711976,0.00009447605,0.000359799,0.0008966673,0.0001608918,0.01211452],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001073811,"threshold_uncertainty_score":0.004236519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05303827460397381,"score_gpt":0.3401152363800458,"score_spread":0.2870769617760719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}