{"id":"W4412515005","doi":"10.1038/s41591-025-03827-z","title":"Polygenic prediction of body mass index and obesity through the life course and across ancestries","year":2025,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Birth, Development, and Health","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Global Health Research; Dalhousie University; Montreal Heart Institute; Université de Montréal; Université Laval","funders":"Center of Innovation Program; Core Research for Evolutional Science and Technology; Institute of Genetics; UCB Pharma; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Biosense Webster; National Center for Advancing Translational Sciences; National Center for Research Resources; National Institute of Environmental Health Sciences; Fogarty International Center; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institute on Aging; National Institute on Alcohol Abuse and Alcoholism; National Key Research and Development Program of China; Health and Social Care Research and Development Division; Departament d'Universitats, Recerca i Societat de la Informació; Det Sundhedsvidenskabelige Fakultet, Københavns Universitet; Sahlgrenska Akademin; Cancer Council Victoria; Canadian Institutes of Health Research; Elizabeth Blackwell Institute for Health Research, University of Bristol; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Mental Health; Helsinki Institute of Life Science, Helsingin Yliopisto; Perelman School of Medicine, University of Pennsylvania; Centers for Disease Control and Prevention; Turun Yliopistosäätiö; Amsterdam Neuroscience; Sygehus Lillebælt; Diabetesforeningen; Heinz Nixdorf Stiftung; Abbott Diagnostics; Provincia autonoma di Bolzano - Alto Adige; Freistaat Sachsen; Xarxa de Bancs de Tumors de Catalunya; Diabetestutkimussäätiö; Wageningen University and Research; H. Lundbeck A/S; Hjartavernd; Institut de Cardiologie de Montréal; Mitsubishi Tanabe Pharma Corporation; Taipei Veterans General Hospital; Takeda Pharmaceutical Company; Fondation du cancer du sein du Québec; Servier; University of Toronto; Syöpäsäätiö; Siemens Healthineers; Amgen; University of Kelaniya; European Commission; Tays; Case Western Reserve University; Landelijke Stichting voor Blinden en Slechtzienden; Deutsche Forschungsgemeinschaft; Taichung Veterans General Hospital; Deutsches Krebsforschungszentrum; Egmont Fonden; Chinese Society of Clinical Oncology; Consejo Nacional de Ciencia y Tecnología; Novo Nordisk Fonden; University of Bristol; Safe Work Australia; Wake Forest School of Medicine; Karl-Franzens-Universität Graz; Diabetesliitto; National Cancer Institute; Peking University; National Institute on Drug Abuse; National Cancer Research Institute; Gratama Stichting; National Institute of Diabetes and Digestive and Kidney Diseases; Instituto de Salud Carlos III; Otsuka Pharmaceutical; Novo Nordisk; Institut National Du Cancer; Wetenschappelijk Onderzoek- en Documentatiecentrum; Radboud Universitair Medisch Centrum; Oulun Yliopisto; Göteborgs Universitet; Lastentautien Tutkimussäätiö; National University Health System; Universität Hamburg; Medical Research Council; Dasman Diabetes Institute; Fundación IMSS; National and Kapodistrian University of Athens; Rigshospitalet; Sydäntutkimussäätiö; Universitair Medisch Centrum Groningen; Oogfonds; Universitetet i Bergen; Umeå Universitet; Instituto Mexicano del Seguro Social; Canadian Cancer Society Research Institute; National Health Research Institutes; Deutsche Krebshilfe; Office of the First Minister and Deputy First Minister; Queen's University; Universität zu Lübeck; Faculty of Medicine and Health, University of Sydney; Oesterreichische Nationalbank; Juho Vainion Säätiö; Ludwig-Maximilians-Universität München; Emil Aaltosen Säätiö; National Institute on Minority Health and Health Disparities; National Research Foundation of Korea; Augustinus Fonden; Korea Institute of Science and Technology; Lundbeckfonden; Faculty of Health and Medical Sciences, University of Western Australia; Fondation Leducq; Lunds Universitet; Samfundet Folkhälsan; Hjerteforeningen; Ministero della Salute; Fundación Marqués de Valdecilla; Alexion Pharmaceuticals; Amsterdam University Medical Centers; Fonds Wetenschappelijk Onderzoek; Nierstichting; KfH-Stiftung Präventivmedizin; Ministerio de Ciencia e Innovación; Generalitat de Catalunya; Vrije Universiteit Amsterdam; Radboud Universiteit; Kela; Yrjö Jahnssonin Säätiö; Economic and Social Research Council; National Natural Science Foundation of China; Universitätsklinikum Regensburg; Danmarks Grundforskningsfond; National Institute of Nursing Research; Universiteit Leiden; Cotswold Foundation; Norges Forskningsråd; Science Foundation Ireland; United Kingdom Clinical Research Collaboration; Stockholms Läns Landsting; GlaxoSmithKline; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Children's Hospital of Philadelphia; Invitae; Murdoch University; Universität Leipzig; Fondation Institut de Cardiologie de Montréal; University of Michigan; Government of the United Kingdom; University of Chinese Academy of Sciences; Ministero dell’Istruzione, dell’Università e della Ricerca; March of Dimes Foundation; British Heart Foundation; Centre for Ageing Research and Development in Ireland; Genome Canada; Boston Scientific Corporation; Scottish Government; National Center for Chronic Disease Prevention and Health Promotion; University of Cambridge; Council of Scientific and Industrial Research, India; Skånes universitetssjukhus; National Institutes of Health; National University of Singapore; Samsung; Prostate Cancer Foundation of Australia; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Rosetrees Trust; Prostate Cancer Canada; University of Notre Dame Australia; Turun Yliopistollinen Keskussairaala; National Medical Research Council; Suomen Kulttuurirahasto; Government of Canada; Health~Holland; Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen; Janssen Scientific Affairs; JST-Mirai Program; National Institute of Biomedical Innovation; Public Health Agency; Eli Lilly and Company; Department for the Economy; Regione Campania; National Research Foundation Singapore; National Research Foundation; Else Kröner-Fresenius-Stiftung; Jan Dekker Stichting; Department of Health, Government of Western Australia; Austrian Science Fund; National Institute for Health and Care Research; Helmholtz Zentrum München; Helsingin Yliopisto; National Eye Institute; Folkhälsanin Tutkimussäätiö; National Center for Global Health and Medicine; Leidos; Cancer Research Institute; U.S. Department of Veterans Affairs; NorthShore University HealthSystem; Stichting Blindenhulp; Swedish Cancer Foundation; Korea National Institute of Health; Center for Translational Molecular Medicine; Karolinska Institutet; Vlaamse regering; Broad Institute; Australian Government; ZonMw; Foundation for Cardiovascular Research; Wellcome Trust; Regeneron Pharmaceuticals; Tampereen Tuberkuloosisäätiö; Pancreatic Cancer UK; Bundesministerium für Bildung und Forschung; Signe ja Ane Gyllenbergin Säätiö; Japan Agency for Medical Research and Development; Sungkyunkwan University; National Science Foundation; University of Thessaly; Gentofte Hospital; Movember Foundation; Massachusetts General Hospital; Scottish Funding Council; Biomedical Research Council; Gilead Sciences; Ministry of Education, Culture, Sports, Science and Technology; Helsingin ja Uudenmaan Sairaanhoitopiiri; Helse Sør-Øst RHF; Royal Marsden NHS Foundation Trust; Southern University of Science and Technology; Bristol-Myers Squibb; Rijksuniversiteit Groningen; Danone; University of Notre Dame; University of Pennsylvania; Medizinische Universität Graz; Bayer; Juvenile Diabetes Research Foundation International; Medical Research Council Canada; Deutsches Zentrum für Herz-Kreislaufforschung; Turun Yliopisto; Chinese Academy of Sciences; Finska Läkaresällskapet; Yale University; Queen's University Belfast; Deutsche Herzstiftung; Atlantic Philanthropies; Victor Chang Cardiac Research Institute; Pfizer; Government of Western Australia; Women and Infants Research Foundation; National Institute of Neurological Disorders and Stroke; Paavo Nurmen Säätiö; Ovarian Cancer Research Fund; China-Japan Friendship Hospital; TrygFonden; Leids Universitair Medisch Centrum; Prostate Cancer Foundation; Sanofi; Vincent Fairfax Family Foundation; National Science Council; Breast Cancer Research Foundation; Agency for Science, Technology and Research; Knut och Alice Wallenbergs Stiftelse; Nederlandse Zuivel Organisatie; National Heart, Lung, and Blood Institute; AstraZeneca; Dalhousie University; Stiftelsen för Strategisk Forskning; Foundation for the National Institutes of Health","keywords":"Body mass index; Obesity; Life course approach; Gerontology; Medicine; Environmental health; Demography; Psychology; Internal medicine; 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