{"id":"W4412523092","doi":"10.1136/bmjopen-2024-089977","title":"Cardiac adverse events associated with remdesivir in COVID-19 patients: a systematic review and meta-analysis of randomised controlled trials","year":2025,"lang":"en","type":"review","venue":"BMJ Open","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Prevention of Organ Failure; University of British Columbia","funders":"Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; HORIZON EUROPE Innovative Europe; China-Japan Friendship Hospital; Institut National de la Santé et de la Recherche Médicale; Canadian Institutes of Health Research; National Institute of Allergy and Infectious Diseases; European Commission; Gilead Sciences","keywords":"Medicine; Meta-analysis; Observational study; Placebo; MEDLINE; Randomized controlled trial; Adverse effect; Systematic review; Subgroup analysis; Relative risk; Clinical trial; Internal medicine; Intensive care medicine; Emergency medicine; Confidence interval; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03370279,0.003568972,0.02678799,0.01121869,0.0008894535,0.004662121,0.002768343,0.002919616,0.004318344],"category_scores_gemma":[0.07447758,0.002013783,0.04533244,0.00986799,0.001129335,0.003078477,0.002258437,0.002575133,0.0003681086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005285098,"about_ca_system_score_gemma":0.008314772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004675729,"about_ca_topic_score_gemma":0.01107107,"domain_scores_codex":[0.9691107,0.01383207,0.01076446,0.002044844,0.003617553,0.0006304156],"domain_scores_gemma":[0.9526151,0.03218428,0.01016699,0.001219954,0.003389185,0.0004244302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001569245,0.00002476591,0.001434681,0.7053202,0.2807572,0.00007912389,0.00008212054,0.0003092327,0.0001233623,0.0001336513,0.0004823014,0.00968405],"study_design_scores_gemma":[0.001236693,0.0003041026,0.002083641,0.108153,0.8849937,0.0001079367,0.00006872764,0.0002256551,0.0001530833,0.0002941163,0.002341279,0.00003808648],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002892671,0.9936715,0.0007747549,0.000250936,0.0001937151,0.001437465,0.0005250639,0.00002811892,0.00022571],"genre_scores_gemma":[0.09521082,0.8878359,0.005725288,0.00122875,0.0003690267,0.008205936,0.0009832005,0.00004195435,0.000399127],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03370279,"threshold_uncertainty_score":0.1782395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3336908914443634,"score_gpt":0.5807995700705287,"score_spread":0.2471086786261654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}