{"id":"W4412542037","doi":"10.5306/wjco.v16.i7.108071","title":"HOXC6-TIMELESS axis: Unveiling novel therapeutic strategies in bladder cancer","year":2025,"lang":"en","type":"letter","venue":"World Journal of Clinical Oncology","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Timeless; Cancer research; Carcinogenesis; Gene silencing; Bladder cancer; Malignancy; Medicine; Biomarker; Cancer; Cell cycle; Apoptosis; Biology; Gene; Pathology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634158,0.0002423717,0.0003858025,0.0003232811,0.0004040953,0.000532055,0.0003152499,0.003482132,0.002135848],"category_scores_gemma":[0.0006739499,0.0001158596,0.000321492,0.0002308408,0.0007160969,0.0009635349,0.0003268225,0.00377918,0.0009686909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006427241,"about_ca_system_score_gemma":0.0003345853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002676693,"about_ca_topic_score_gemma":0.0005428003,"domain_scores_codex":[0.9998968,0.00002271571,0.00001230649,0.00001797736,0.00002690484,0.00002333709],"domain_scores_gemma":[0.9997944,0.00008958081,0.00001832989,0.00001719983,0.00003034102,0.00005001849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001216872,0.000315704,0.01572021,0.001764002,0.00009448114,0.09403133,0.0003804382,0.001222443,0.05573148,0.02553233,0.3716672,0.4323234],"study_design_scores_gemma":[0.0003152791,0.0005938887,0.01089504,0.00037615,0.0000978924,0.1567852,0.0004137249,0.003677837,0.01450621,0.03195328,0.7803205,0.0000650463],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.07201497,0.1813154,0.007294141,0.7017585,0.01874741,0.00009895077,0.0002589303,0.0003890184,0.01812266],"genre_scores_gemma":[0.4724686,0.1359342,0.01186963,0.2508779,0.09602405,0.0001369653,0.0004313016,0.0001088998,0.03214844],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.003482132,"threshold_uncertainty_score":0.007145107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1396163993152089,"score_gpt":0.4717351489778968,"score_spread":0.332118749662688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}