{"id":"W4412546169","doi":"10.1111/pbi.70278","title":"Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for <scp>SARS</scp> ‐ <scp>CoV</scp> ‐2 Expressed in Plants","year":2025,"lang":"en","type":"article","venue":"Plant Biotechnology Journal","topic":"Transgenic Plants and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Immunogenicity; Immune system; Biology; Antibody; Antigen; Vaccination; Virology; Immunology; Context (archaeology); Cholera toxin; Microbiology; Immunity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000921485,0.0002558781,0.000168147,0.0001117322,0.0001525628,0.0002169295,0.0002263515,0.0003004301,0.0007444761],"category_scores_gemma":[0.00007832069,0.0001225819,0.0003567072,0.0001468405,0.0001466628,0.0001564211,0.0001407084,0.0005276398,0.0004165834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004326179,"about_ca_system_score_gemma":0.0002576588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007572814,"about_ca_topic_score_gemma":0.000690278,"domain_scores_codex":[0.9999551,0.000007078198,0.000003094646,0.000009295948,0.00001311167,0.00001233309],"domain_scores_gemma":[0.9999542,0.000004662641,0.00001583414,0.000004117243,0.000007542044,0.00001360934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006240259,0.00002193878,0.00005961031,0.00002684532,0.000003814672,0.00004253949,0.0000124413,0.0007251963,0.9981251,0.0001427941,0.00002217352,0.0007551978],"study_design_scores_gemma":[0.00004547603,0.0008706433,0.001487031,0.000007598836,0.0000288682,0.0002136675,0.0000302754,0.003770968,0.9876961,0.0000926954,0.005745191,0.00001167151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991362,0.0004726473,0.006771393,0.0001111599,0.00001550696,0.00007520745,0.0002068407,0.000033813,0.0009514361],"genre_scores_gemma":[0.9879176,0.0004911361,0.008803046,0.00005988628,0.000007223179,0.00004533103,0.0007026055,0.00002272143,0.001950548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007572814,"threshold_uncertainty_score":0.00313884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01331031153705525,"score_gpt":0.2485226683260306,"score_spread":0.2352123567889754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}