{"id":"W4412600394","doi":"10.25251/gdd40x24","title":"Long-term Efficacy and Safety of Ritlecitinib in Adults and Adolescents with Alopecia Areata: 3-year Results from the ALLEGRO-LT Phase 3, Open-label Study","year":2025,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Hair Growth and Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"LEO Pharma; Eli Lilly and Company; Concert Pharmaceuticals; L'Oreal USA; Sanofi; Pfizer","keywords":"Alopecia areata; Open label; Dermatology; Medicine; Term (time); Pediatrics; Adverse effect; Internal medicine; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002286957,0.0002548766,0.0008601738,0.0001863666,0.0002634635,0.0006714557,0.0002499147,0.0004288402,0.001273293],"category_scores_gemma":[0.0009979968,0.0001187465,0.001136982,0.0002607633,0.0002023792,0.0005438288,0.0001822137,0.000925138,0.0003506242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004240121,"about_ca_system_score_gemma":0.0004421742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006664851,"about_ca_topic_score_gemma":0.002385199,"domain_scores_codex":[0.9993649,0.0002330617,0.00006362607,0.00009548081,0.0001663503,0.00007660283],"domain_scores_gemma":[0.9984823,0.0003106567,0.0006635884,0.00007295186,0.0001990738,0.0002715227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1363704,0.008604329,0.4527326,0.003051409,0.005861113,0.0007445006,0.0008090033,0.002398032,0.02618778,0.000189855,0.01082553,0.3522255],"study_design_scores_gemma":[0.02683347,0.1002966,0.8516981,0.0003293338,0.002928304,0.001789384,0.0002053826,0.001401253,0.004068199,0.0001347382,0.01025399,0.00006119766],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852276,0.01081376,0.0002734131,0.0002321669,0.00003782254,0.0002163287,0.001635338,0.00003103267,0.001532546],"genre_scores_gemma":[0.9950789,0.001816378,0.000320068,0.0003187278,0.00005771973,0.0001221132,0.001896492,0.000005538434,0.0003839857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002286957,"threshold_uncertainty_score":0.01209474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527015727632881,"score_gpt":0.3098022576172259,"score_spread":0.2945321003408971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}