{"id":"W4412619980","doi":"10.1007/s12033-025-01480-y","title":"Characterization of a Phage Display-Selected scFv Against Neuropilin 1 (NRP1) Isolated from a Naïve Human Library","year":2025,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Neuropilin 1; Phage display; Peptide library; Molecular biology; Biology; Computational biology; Antibody; Chemistry; Genetics; Peptide sequence; Gene; VEGF receptors; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337427,0.0003133588,0.0003526997,0.0002706024,0.0001776543,0.0004340436,0.0002548302,0.0002523811,0.002069063],"category_scores_gemma":[0.0001924364,0.0001287498,0.000263745,0.0003028394,0.00008732911,0.0001049727,0.0002026029,0.0005009901,0.0009139816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002643195,"about_ca_system_score_gemma":0.0001612242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001176626,"about_ca_topic_score_gemma":0.001064171,"domain_scores_codex":[0.9998525,0.00001645596,0.000007578247,0.0000280616,0.00004656837,0.00004870698],"domain_scores_gemma":[0.9998906,0.00003511747,0.000008446554,0.000009922761,0.00002189257,0.0000339568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005090324,0.00002757758,0.0001382118,0.00001156654,0.000004263491,0.00003299405,0.000009523405,0.00005435168,0.9986725,0.00002582612,0.00004616843,0.0009260548],"study_design_scores_gemma":[0.00001778614,0.000262763,0.007116573,0.000005155361,0.00002548758,0.000386703,0.00003090097,0.001795888,0.987591,0.00002681075,0.002735313,0.000005748276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864196,0.0004313441,0.008919273,0.0001104333,0.00002780668,0.00007162065,0.001666128,0.0001294711,0.00222443],"genre_scores_gemma":[0.9753214,0.0005415333,0.005548417,0.0002003746,0.00001596231,0.0000588141,0.007678621,0.00007465157,0.01056025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002069063,"threshold_uncertainty_score":0.006921709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003957187384404739,"score_gpt":0.2351146542084389,"score_spread":0.2311574668240342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}