{"id":"W4412630188","doi":"10.1097/qad.0000000000004309","title":"Blood pressure, weight change and incident hypertension after switching to dolutegravir in treatment-experienced people with HIV","year":2025,"lang":"en","type":"article","venue":"AIDS","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hypertension Canada","funders":"","keywords":"Dolutegravir; Medicine; Blood pressure; Efavirenz; Cohort; Lamivudine; Prospective cohort study; Cohort study; Internal medicine; Weight change; Human immunodeficiency virus (HIV); Weight loss; Viral load; Antiretroviral therapy; Obesity; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000410709,0.0001411841,0.0002575937,0.0002150585,0.00008165271,0.0000122651,0.00003391731,0.00006003768,0.00002158964],"category_scores_gemma":[0.00001079164,0.00009140575,0.00002179541,0.0003869607,0.000009980144,0.0000688471,0.00003318119,0.00007829758,0.0000186229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005060576,"about_ca_system_score_gemma":0.00005510631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001446228,"about_ca_topic_score_gemma":0.0004424375,"domain_scores_codex":[0.999213,0.00002250519,0.0001630102,0.0002965988,0.00009943505,0.0002053877],"domain_scores_gemma":[0.9994931,0.00003465757,0.00002557437,0.0002770894,0.0000416401,0.000127927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002603919,0.0004827023,0.9855621,0.0000408146,0.0001091675,0.00008006846,0.00355733,6.618296e-7,0.0005484406,0.0001430798,0.00003224315,0.009182937],"study_design_scores_gemma":[0.003321903,0.0009471797,0.9903946,0.0004127315,0.0004359458,0.00004817959,0.0001865199,0.0001208581,0.0005472791,0.00003203722,0.003460562,0.00009220764],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942293,0.002242272,0.00006803151,0.00186371,0.00003652168,0.0008921981,0.00000465759,0.0000338611,0.0006294864],"genre_scores_gemma":[0.9956154,0.0002121762,0.001544315,0.0008162314,0.00002490775,0.0009100256,0.00001227982,0.00001180301,0.000852923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009090729,"threshold_uncertainty_score":0.3727418,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0164629017477478,"score_gpt":0.2822927493347969,"score_spread":0.2658298475870491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}