{"id":"W4412638930","doi":"10.1038/s41698-025-01053-x","title":"Molecular subtyping of endometrial carcinoma cell lines uncovers subtype-specific targetable vulnerabilities","year":2025,"lang":"en","type":"article","venue":"npj Precision Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia Hospital; BC Children's Hospital; Spinal Cord Injury BC; University of British Columbia; Vancouver Coastal Health","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of British Columbia; Terry Fox Research Institute; Canadian Cancer Society; VGH and UBC Hospital Foundation","keywords":"Subtyping; Cancer research; Carcinoma; Biology; Internal medicine; Computer science; Medicine; Programming language","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005995708,0.0001755021,0.0006356366,0.000598859,0.00008763472,0.0000137331,0.0001694115,0.0002404681,0.0005051407],"category_scores_gemma":[0.0004821482,0.0001374626,0.0001885065,0.0007724214,0.0002026192,0.00006874034,0.0001376165,0.0002997331,0.00002664427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004682727,"about_ca_system_score_gemma":0.0009560204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001496622,"about_ca_topic_score_gemma":0.00001209936,"domain_scores_codex":[0.9981996,0.0002175484,0.0004786008,0.0003921966,0.0003421308,0.000369893],"domain_scores_gemma":[0.9979467,0.001031045,0.0001187017,0.0004131323,0.0003797467,0.0001106234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02868306,0.002776392,0.1629664,0.001094285,0.0005073334,0.0006147854,0.001314151,0.000685722,0.6253687,0.004076401,0.0455567,0.126356],"study_design_scores_gemma":[0.01202069,0.002101401,0.005347579,0.0001173708,0.0001164829,0.00001083075,0.0005091762,0.0001570832,0.7811084,0.001663519,0.1966915,0.0001559144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9492031,0.0127693,0.0007193427,0.0008841018,0.001101085,0.0007886262,0.00002444628,0.00003678524,0.03447324],"genre_scores_gemma":[0.9904938,0.001197776,0.001696009,0.0001228509,0.0001318566,0.00005519121,0.00005578483,0.00001805989,0.006228643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1576189,"threshold_uncertainty_score":0.5605561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03006745265890889,"score_gpt":0.3375247825362829,"score_spread":0.3074573298773741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}