{"id":"W4412650222","doi":"10.1093/humrep/deaf146","title":"Double trouble: the impact of repeated biopsy and vitrification on euploid blastocyst transfer outcomes","year":2025,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre; Ottawa Fertility Centre","funders":"European Society of Human Reproduction and Embryology","keywords":"Vitrification; Blastocyst Transfer; Blastocyst; Andrology; Medicine; Gynecology; Biology; Embryo; Genetics; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01400322,0.0003814822,0.001007056,0.0006498502,0.0005950675,0.002351438,0.00126189,0.001430656,0.006266849],"category_scores_gemma":[0.09188138,0.0001910344,0.002710555,0.0007704778,0.0006497722,0.001771713,0.00233808,0.00277337,0.0006701576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002062067,"about_ca_system_score_gemma":0.003941198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007164104,"about_ca_topic_score_gemma":0.008610308,"domain_scores_codex":[0.9898712,0.005013297,0.0009104281,0.001173467,0.002281611,0.00075004],"domain_scores_gemma":[0.9333833,0.04246275,0.01218854,0.002310946,0.004236766,0.005417691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01706058,0.0006509084,0.3591154,0.001757348,0.002867972,0.0005302434,0.0007206181,0.0009068199,0.0004976527,0.001258512,0.01885764,0.5957763],"study_design_scores_gemma":[0.002132488,0.0189024,0.8956307,0.007704276,0.009648341,0.003713417,0.002662895,0.003794815,0.00338332,0.006881336,0.04520823,0.0003377523],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8145847,0.09781762,0.004896995,0.05592874,0.004735687,0.0003918756,0.00574107,0.000278036,0.01562528],"genre_scores_gemma":[0.9834349,0.005249683,0.002199996,0.004996085,0.0008801494,0.0001498862,0.001296576,0.0001088783,0.001683805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01400322,"threshold_uncertainty_score":0.07405698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03350997268959938,"score_gpt":0.3364222371833592,"score_spread":0.3029122644937598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}