{"id":"W4412658536","doi":"10.1016/j.breast.2025.104547","title":"Hormonal factors predictive of fertility in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy in POSITIVE trial","year":2025,"lang":"en","type":"article","venue":"The Breast","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; ECOG-ACRIN Cancer Research Group; National Institutes of Health; Rising Tide Foundation; American College of Radiology Imaging Network; NRG Oncology; Fonds De La Recherche Scientifique - FNRS; Fondazione Umberto Veronesi; Gateway for Cancer Research; Rising Tide Foundation for Clinical Cancer Research; Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung; Breast Cancer Research Foundation","keywords":"Medicine; Ovarian reserve; Pregnancy; Anti-Müllerian hormone; Hormone; Prolactin; Follicle-stimulating hormone; Breast cancer; Gynecology; Infertility; Fertility; Obstetrics; Cancer; Internal medicine; Population; Luteinizing hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002363973,0.0001844395,0.0004361578,0.0001248067,0.00003933859,0.000003562276,0.0001428706,0.00005969613,0.00003952304],"category_scores_gemma":[0.000073503,0.0001008849,0.00006124881,0.0003740937,0.000196959,0.00007359943,0.0000787419,0.0002860382,8.112066e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001948299,"about_ca_system_score_gemma":0.0001456685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001227059,"about_ca_topic_score_gemma":0.0002031539,"domain_scores_codex":[0.9985843,0.0002119162,0.0003674287,0.0004171937,0.0001674876,0.0002517039],"domain_scores_gemma":[0.9991818,0.00009408161,0.00009886277,0.0003595168,0.0002164632,0.00004929402],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2645919,0.0007530198,0.7175928,0.00001637236,0.0001030706,0.000001726131,0.0009644346,0.000004993584,0.0002835393,0.000004101415,0.000005320351,0.01567876],"study_design_scores_gemma":[0.01929069,0.000865618,0.9774991,0.0008646583,0.00002975781,0.000003520451,0.0002046832,0.000009986099,0.001105582,0.00004563869,0.000001917855,0.00007888927],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959405,0.0002737673,0.00002265866,0.001045668,0.0001293073,0.001967977,0.0003110311,0.00001451906,0.0002945458],"genre_scores_gemma":[0.999649,0.000009901158,0.000007488027,0.00008155972,0.00003638929,0.0001137643,0.00002844367,0.000008438064,0.00006501083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2599063,"threshold_uncertainty_score":0.4113967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498113598616576,"score_gpt":0.2908316096341852,"score_spread":0.2758504736480195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}