{"id":"W4412659824","doi":"10.1038/s41467-025-62259-y","title":"Somites are a source of nephron progenitors in zebrafish","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Health and Medical Research Council; Canadian Institutes of Health Research; Royal Society Te Apārangi; National Institutes of Health; University of Auckland; U.S. Department of Health and Human Services; Government of Canada; Marsden Fund; Harvard University; Universität Basel","keywords":"Somite; Zebrafish; Mesoderm; Paraxial mesoderm; Biology; Nephron; Pronephros; Kidney development; Intermediate mesoderm; Cell biology; Vertebrate; Progenitor; Kidney; Developmental biology; Progenitor cell; Anatomy; Embryonic stem cell; Stem cell; Embryogenesis; Genetics; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001200418,0.0002428656,0.0002262865,0.0005141108,0.0004090329,0.0003785074,0.0002816404,0.0003239278,0.002358902],"category_scores_gemma":[0.0001502436,0.0004109655,0.0002384191,0.000143427,0.000368675,0.0003058749,0.0005229022,0.0009445916,0.000894692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005493985,"about_ca_system_score_gemma":0.0005268338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004511566,"about_ca_topic_score_gemma":0.009966599,"domain_scores_codex":[0.9999068,0.000004577502,0.00000592713,0.00002105414,0.00004770872,0.00001398668],"domain_scores_gemma":[0.9998848,0.00001749147,0.00003174196,0.00001042772,0.00001444008,0.00004111129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000112059,0.000003933215,0.0006525554,0.00005868508,0.000004423912,0.0002125736,0.00007046597,0.0001514729,0.9925864,0.002097129,0.0001642024,0.003886164],"study_design_scores_gemma":[0.00004921116,0.0001800331,0.03429845,0.00006597433,0.00004367983,0.001058905,0.0001447459,0.001637585,0.919072,0.0009562911,0.04245638,0.00003682001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9125705,0.00501772,0.03794295,0.0008191656,0.0001638988,0.0001239154,0.003754656,0.001012103,0.03859507],"genre_scores_gemma":[0.9295205,0.002939005,0.02198993,0.0002599803,0.00003338591,0.0001031667,0.001416951,0.0003731117,0.04336402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004511566,"threshold_uncertainty_score":0.008970618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00517396664784428,"score_gpt":0.268396344398196,"score_spread":0.2632223777503517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}