{"id":"W4412696634","doi":"10.1002/adhm.202501952","title":"Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies","year":2025,"lang":"en","type":"article","venue":"Advanced Healthcare Materials","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; St. Joseph’s Healthcare Hamilton; McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Inhalation; Macrophage; Lung; Pharmacology; Materials science; In vitro; Medicine; Chemistry; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003497583,0.0001940587,0.0006848186,0.0002044131,0.0001464188,0.00002126635,0.0000813411,0.0001933569,0.0000218146],"category_scores_gemma":[0.0002932806,0.0001673289,0.00005475263,0.000265528,0.0003068878,0.0001458955,0.00005586756,0.00009266273,0.000001474156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005571454,"about_ca_system_score_gemma":0.0002556643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003481518,"about_ca_topic_score_gemma":0.00002887284,"domain_scores_codex":[0.9985269,0.0001242976,0.0005410383,0.0003860528,0.0001226263,0.0002990682],"domain_scores_gemma":[0.9987329,0.0001512151,0.0002404707,0.0003639281,0.0004292434,0.00008220837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008422014,0.0001250512,0.001196804,0.002441841,0.00009137706,0.000001941516,0.0002427066,0.000001480324,0.983429,0.0008902511,0.000007304601,0.003150258],"study_design_scores_gemma":[0.005130732,0.0006869665,0.002276469,0.0003261744,0.00007444563,0.000003230622,0.0007308941,0.000003177794,0.989759,0.0004058851,0.0004758443,0.0001271708],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917612,0.001277826,0.0001219326,0.00454736,0.0004410375,0.00156314,0.0001301538,0.0001293793,0.00002795858],"genre_scores_gemma":[0.9976468,0.0001728111,0.001686539,0.0002176494,0.00004375252,0.000146899,0.00002445414,0.00002055699,0.00004054251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006330039,"threshold_uncertainty_score":0.6823475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02152271184192266,"score_gpt":0.3337415182747261,"score_spread":0.3122188064328035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}